Clindamycin Hydrochloride
Basic information of clindamycin hydrochloride
CAS No.:[21462-39-5]
Chemical Name:Methyl 7-chloro-6,7,8-trideoxy-6- (1-methyl-trans-4-propyl-L-2- pyrrolidinecarboxamido)-1- thio-L-threo-a-D-galacto- octopyranoside monohydrochloride
Molecular Formula:C18H33ClN2O5S
Molecular Weight:461.44
Structural Formula:
Property:white crystalline powder,odorless. Very soluble in water, soluble in methanol or pyridine, slightly soluble in ethanol, almost insoluble in acetone or chloroform
Usage of clindamycin hydrochloride
Usage:antibiotic and anti-infective material, derivant of Lincomycin. Its mechanism is through the body of DNA with the bacteria nucleoprotein 50s subunits combination, Interfere the extension of peptide chains, effects bacteria protein synthesis for the sake of sterilization, bacteriostasis.
Package and storage of clindamycin hydrochloride
Package:25KG/Drum
Storage:sealed and preserved in tight container
Standard of clindamycin hydrochloride
Executive Standard: CP2010, USP32, BP, EP, CEP No.: R0-CEP 2010-281-REV 00
Clindamycin Hydrochloride is the hydrochloride salt form of clindamycin, a semi-synthetic, chlorinated broad spectrum antibiotic produced by chemical modification of lincomycin. Clindamycin hydrochloride is used as a solid in capsules.
An antibacterial agent that is a semisynthetic analog of LINCOMYCIN.
IUPAC
(2S,4R)-N-[(1S,2S)-2-chloro-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylsulfanyloxan-2-yl]propyl]-1-methyl-4-propylpyrrolidine-2-carboxamide;hydrochloride
SMILES
CCC[CH]1C[CH](N(C1)C)C(=O)N[CH]([CH]2[CH]([CH]([C@H]([C@H](O2)SC)O)O)O)[C@H](C)Cl.Cl