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Pharmaceutical Intermediates

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CAS:89-25-8
Molecular Formula:C10H10N2O
PMP; 1,3,5-PMP; Edaravone; 3-Methyl-1-Phenyl-1H-Pyrazol-5(4H)-one; Phenyl Methyl Pyrazolone; 1-Phenyl-3-Methyl-5-Pyrazalone; 5-Methyl-2-Phenyl-1,2-Dihydropyrazol-3-One; 1-Phenyl-3-Methyl-5-OXO-2-Pyrazoline; 3-Methyl-1-Phenyl-2-Pyrazolin-5-ONE FOR Synthesis; Edaravone (MCI-186); 3-Methyl-1-Phenyl-2-Pyrazoline-5-one; 3H-Pyrazol-3-one, 2,4-Dihydro-5-Methyl-2-Phenyl-; 3-Methyl-1-Phenyl-2-Pyrazolin-5ONE; 5-Methyl-2-Phenyl-1,2-Dihydropyrazol-3-ONE Edaravone; 3-Methyl-1-Phenyl-2-Pyrazolin-5-one; c.i. Developer 1; 1-Phenyl-3-Methyl-5- Pyrazolone; 1-Phenyl-3-Methyl-5-Pyrazole; 5-Methyl-2-Phenyl-2,4-Dihydro-3H-Pyrazol-3-one; 1-Pheny-3-Methyl-5-Pyrazolone (PMP)
Brief Introduction
Mainly used in the synthesis of pharmaceutical intermediates, but also used in dyes and color film dyes, pesticides and organic synthesis industry.
CAS:79-31-2
Molecular Formula:C4H8O2
2-Methyl Propionic Acid; _|_; Alpha Isobutyric Acid; Isobutanoic Acid; Iso Butyric Acid
Brief Introduction
Isobutyric acid is a branched fatty acid comprising propanoic acid carrying a methyl branch at C-2. It has a role as a volatile oil component, a plant metabolite and a Daphnia magna metabolite. It is a branched-chain saturated fatty acid, a methyl-branched fatty acid and a fatty acid 4:0. It is a conjugate acid of an isobutyrate.
CAS:124-41-4
Molecular Formula:CH3NaO
Sodium Methylate; Sodium Methanolate; Methanol Sodium Salt; SMO; Feldalatnm; Methanol, Sodium Salt; Methoxysodium; Methylatedesodium(French)
Brief Introduction
Sodium methoxide is a kind of alkoxide formed from methanol, which is a strong base commonly used in organic synthesis. There are two forms of sodium methoxide: solid and liquid. The solid is pure sodium methoxide, and the liquid is methanol solution of sodium methoxide. The content of sodium methoxide is 27.5 ~ 31%. Liquid sodium methoxide is colorless or yellowish viscous liquid, sensitive to oxygen, flammable and explosive. Easy to absorb moisture. It dissolves in methanol and ethanol, decomposes into methanol and sodium hydroxide in water, and decomposes in air above 126.6 ℃. Insoluble in benzene and toluene. It has strong irritation and strong corrosiveness. It is used as condensation agent, strong basic catalyst and methoxylation agent for the preparation of vitamin B1, a, sulfadiazine and other drugs. A small amount is used in pesticide production. It can also be used as a catalyst for the treatment of edible fats and oils, especially lard. It can also be used as analytical reagent. Solid sodium methoxide is a colorless amorphous powder, sensitive to oxygen, flammable, soluble in methanol and ethanol, decomposed into methanol and sodium hydroxide in water, and decomposed in air above 126.6 ℃. It is mainly used in the production of sulfonamides, VB6 and VA. Sodium methoxide is also a catalyst for organic synthesis, which is used in pesticide production and oil processing industry.
CAS:540737-29-9
Molecular Formula:C22H28N6O8
Tofacitinib (Citrate); 3-((3R,4R)-4-Methyl-3-(Methyl(7H-Pyrrolo[2,3-d]Pyrimidin-4-yl)Amino)Piperidin-1-yl)-3-Oxopropanenitrile 2-Hydroxypropane-1,2,3-Tricarboxylate; Tofacitinibcitrate; 2-Hydroxypropane-1,2,3-Tricarboxylic acid; 3-[(3R,4R)-4-Methyl-3-[Methyl({7H-Pyrrolo[2,3-d]Pyrimidin-4-yl})Amino]Piperidin-1-yl]-3-Oxopropanenitrile
Brief Introduction
Tofatinib citrate combined with methotrexate in the treatment of active rheumatoid arthritis with insufficient response to tumor necrosis factor inhibitors.
CAS:95-57-8
Molecular Formula:C6H5ClO
2-Chlorophenol; Septi-Kleen; O-Chloro-Pheno; 2-Chlorphenol; 2-Chloro-Pheno; O-Cl Phenol; Phenol,2-Chloro; O-Chlorophenol; Chlorophenolate; O-Monochlorophenol; Chloro-2Phenol; Ortho-Chlorophenol; OCP
Brief Introduction
2-Chlorophenol is mainly used in pesticide, medicine, dyestuff, plastics and other industries. It is also used as denaturant of alcohol and selective solvent of refined mineral oil. It can also be used for microscope analysis and plant growth promoter. It can be used to synthesize dyes and react with dilute nitric acid to form mononitro and dinitro compounds, which are dye intermediates. It can further synthesize a variety of dyes, such as neutral brilliant green BL, etc. It is also used as denaturant for alcohol and selective solvent for refining mineral oil. In the pesticide industry, it is mainly used for the synthesis of Triadimefon, imipramine, wool fungicide, anti falling hormone (multifunctional plant growth regulator), propafenone (internal insecticide), tetraphos, insecticide, acaricide (Non internal acaricide), acaricide and dicofofen; In the pharmaceutical industry, it is used for carboxylation of sodium 5-chloro-2-hydroxybenzoate, synthesis of antomin, p-chlorophenoxyisobutyric acid and other drugs; It is also used in the synthesis of antioxidant BHA.
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