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Jiangxi Ruyu Technology Development Co., Ltd.
Jiangxi Ruyu Technology Development Co., Ltd.
18 YRS
Jiangxi, China
Main Products:
(2S,4S)-4-Nitrobenzyl 2-(Dimethylcarbamoyl)-4-Mercaptopyrrolidine-1-Carboxylate / 3-((2S,4S)-4-Mercapto-1-(((4-Nitrobenzyl)Oxy)Carbonyl)Pyrrolidine-2-Carboxamido)Benzoic Acid / Sodium Azide
Jiangxi, China
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(2S,4S)-4-Nitrobenzyl 2-(Dimethylcarbamoyl)-4-Mercaptopyrrolidine-1-Carboxylate / CAS 96034-64-9
OVERVIEW
Uses
Packaging
25 KG/Fibre Drum
Lead Time
14-30 days
Max Capacity
30 MT/Year
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DESCRIPTION
(2S,4S)-4-Nitrobenzyl 2-(Dimethylcarbamoyl)-4-Mercaptopyrrolidine-1-Carboxylate
Molecular formula: C15H19N3O5S
Molecular weight: 353.39
CAS NO: 96034-64-9
Structural type: 
Storage: 0-8 degrees, light proof seal (with black lining)
Purpose: Meropenem synthesis
Quality standard:
Item | Index |
Appearance | White or off white powder |
Content | ≥98.0%(HPLC) |
Melting point | 117-119.5℃ |
Specific rotation | [α]D20= +9.60- +9.75 (c=1.01, CHCl3) |
Water content | ≤3% |
Typical Properties
Summary
Meropenem side chain is a kind of pharmaceutical intermediate, which is mainly used in the production of antibiotic meropenem. For the treatment of patients with severe infection or multi drug resistant bacteria infection, both G + bacteria and G - bacteria have good curative effect, but it is not suitable for the treatment of methicillin-resistant Staphylococcus aureus. It is also not suitable for infection of other carbapenem resistant bacteria, such as some Acinetobacter. Aminoglycosides (e.g. amikacin) should be used in combination with anti Pseudomonas aeruginosa.
CAS No.
96034-64-9
Formula
C15H19N3O5S
Molecular Mass
353.39300
Exact Mass
353.10500
PSA
134.47000
Logp
134.47000
IUPAC
(4-nitrophenyl)methyl (2S,4S)-2-(dimethylcarbamoyl)-4-sulfanylpyrrolidine-1-carboxylate
SMILES
CN(C)C(=O)C1CC(CN1C(=O)OCC2=CC=C(C=C2)[N+](=O)[O-])S
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Pharmaceutical Intermediates
API & Intermediate > Antibiotics
API & Intermediate > Antibiotics
Chemical and Physical Properties
Melting Point
117.0 to 121.0 °C
Density
1.36±0.1 g/cm3
Boiling Point
555.8±50.0 °C
Flash Point
289.9ºC
Appearance
White crystalline solid
Acidity and Basicity
acidness oxidizability
Export information
HS Code
29339900
Export Rebate
13%
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