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Changzhou Huaren Chemical Co.,Ltd.

24 YRS

Jiangsu, China

CNY 12.8 Million

95904 m²

50-100 people

Main Products: Fingolimod Hydrochloride / Rapamycin / (S)-(+)-1,2-Propanediol

Jiangsu, China

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Rapamycin / CAS 53123-88-9

≥95%

OVERVIEW

Packaging

25 KG/Fibre Drum

Lead Time

14-30 days

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DESCRIPTION

Typical Properties

Rapamycin was developed as early as 1970s. It was initially used as a low toxic antifungal drug. In 1977, rapamycin was found to have immunosuppressive effect. In 1989, rapamycin began to be used as a new drug for the treatment of organ transplantation rejection. From the effect of animal experiment and clinical application, rapamycin is a new immunosuppressant with good curative effect, low toxicity and no nephrotoxicity. Now it is often used as a drug to maintain the immune ability of transplanted organs (especially kidney transplantation) to slow down the immune rejection after organ transplantation. However, scientists recently found another use: it can be used to treat Alzheimer's disease (Alzheimer's disease).

CAS No.

53123-88-9

Formula

C51H79NO13

Molecular Mass

914.17200

Exact Mass

913.55500

PSA

195.43000

Logp

6.11850

IUPAC

(1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone

SMILES

C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)C)/C)O)OC)C)C)/C)OC

Matter Classification

organic

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