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Emeishan Hongsheng Pharmaceutical Co.,Ltd.
Emeishan Hongsheng Pharmaceutical Co.,Ltd.
13 YRS
Sichuan, China
Main Products:
Sesamol / Azilsartan / Candesartan Cilexetil / Ethyl 1-((2'-Cyano-[1,1'-Biphenyl]-4-Yl)Methyl)-2-Ethoxy-1H-Benzo[D]Imidazole-7-Carboxylate / Methyl 1-((2'-Cyano-[1,1'-Biphenyl]-4-Yl)Methyl)-2-Ethoxy-1H-Benzo[D]Imidazole-7-Carboxylate / 2,3,4,6-Tetrakis-O-Trimethylsilyl-D-Gluconolactone / (S)-4-iodo-1-Chloro-2-(4-Tetrahydrofuran-3-Yloxy-Benzyl)-Benzene / Acetoxy Empagliflozin / (2-Chloro-5-Iodophenyl)(4-Fluorophenyl)Methanone / 4-Bromo-1-Chloro-2-(4-Ethoxybenzyl)Benzene / [(2R,3R,4R,5S,6S)-3,4,5-Triacetyloxy-6-[4-Chloro-3-[(4-Ethoxyphenyl)Methyl]Phenyl]Oxan-2-Yl]Methyl Acetate / (R)-3-(Boc-Amino)Piperidine / 3-Methylxanthine / 8-Bromo-3-Methyl-1H-Purine-2,6(3H,7H)-Dione / 8-Bromo-7-(But-2-Yn-1-Yl)-3-Methyl-1H-Purine-2,6(3H,7H)-Dione / 2-(Chloromethyl)-4-Methylquinazoline / 1-Bromo-2-Butyne / 8-Bromo-7-but-2-ynyl-3-Methyl-1-(4-Methyl-Quinazolin-2-Ylmethyl)-3,7-Dihydro-Purine-2,6-Dione
Sichuan, China
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Sesamol
Azilsartan
Candesartan Cilexetil
Ethyl-2-Ethoxy-1-[[(2'-Cyanobiphenyl-4-yl) Methyl] Benzimidazole]-7-Carboxylate
Methyl 1-((2'-Cyano-[1,1'-Biphenyl]-4-Yl)Methyl)-2-Ethoxy-1H-Benzo[D]Imidazole-7-Carboxylate
2,3,4,6-Tetrakis-O-Trimethylsilyl-D-Gluconolactone
(3S)-3-[4-[(2-Chloro-5-Iodophenyl)Methyl]Phenoxy]Tetrahydro-Furan
Acetoxy Empagliflozin
(2-Chloro-5-Iodophenyl)(4-Fluorophenyl)Methanone
5-Bromo-2-Chloro-4'-Ethoxydiphenylmethane
(2R,3R,4R,5S,6S)-2-(Acetoxymethyl)-6-(4-Chloro-3-(4-Ethoxybenzyl)Phenyl)Tetrahydro-2H-Pyran-3,4,5-Triyl Triacetate
(R)-3-(Boc-Amino)Piperidine
2,6-Dihydroxy-3-Methylpurine
8-Bromo-3-Methyl-3,7-Dihydropurine-2,6-Dione
8-Bromo-7-(But-2-Yn-1-Yl)-3-Methyl-1H-Purine-2,6(3H,7H)-Dione
2-(Chloromethyl)-4-Methylquinazoline
1-Bromo-2-Butyne
8-Bromo-7-but-2-ynyl-3-Methyl-1-(4-Methyl-Quinazolin-2-Ylmethyl)-3,7-Dihydro-Purine-2,6-Dione
(2-Chloro-5-Iodophenyl)(4-Fluorophenyl)Methanone / CAS 945065-86-2
OVERVIEW
Packaging
25 KG/Fibre Drum
Lead Time
14-30 days
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DESCRIPTION
(2-Chloro-5-Iodophenyl)(4-Fluorophenyl)Methanone
English Name: (2-Chloro-5-Iodophenyl)(4-Fluorophenyl)Methanone
CAS No.: 945065-86-2
Application: intermediate for synthesis of englitazin.
Typical Properties
Summary
(2-chloro-5-iodophenyl) (4-fluorophenyl) ketone is an intermediate for the synthesis of epallegin. Epallegin is a type 2 sodium glucose cotransporter inhibitor jointly developed by Boehringer Ingelheim and Eli Lilly. Sglt-2 inhibitor is a new hypoglycemic drug. It mainly reduces the reabsorption of glucose by the kidney and increases the excretion of glucose in urine by inhibiting sglt-2 expressed in the kidney, so as to reduce the level of plasma glucose. Its hypoglycemic effect does not depend on β Cell function and insulin resistance.
CAS No.
945065-86-2
Formula
C13H7ClFIO
Molecular Mass
360.55000
Exact Mass
359.92100
PSA
17.07000
Logp
4.31470
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Pharmaceutical Intermediates
Chemical and Physical Properties
Density
1.752
Boiling Point
415℃
Flash Point
205℃
Appearance
White powder
Export information
HS Code
29420000
Export Rebate
13%
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