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Zhejiang Langhua Pharmaceutical Co.,Ltd.
Zhejiang Langhua Pharmaceutical Co.,Ltd.
24 YRS
Zhejiang, China
Main Products:
Ciprofloxacin / Ciprofloxacin Hydrochloride Hydrate / Enrofloxacin / Levofloxacin Hemihydrate / Canrenone / Spironolactone / Olanzapine / Zidovudine / Empagliflozin / Gsk1349572 Sodium Salt
Zhejiang, China
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Spironolactone / CAS 52-01-7
OVERVIEW
Packaging
25 KG/Fibre Drum
Lead Time
14-30 days
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DESCRIPTION
Spironolactone
CAS:52-01-7
Molecular formula：C24H32O4S
Molecular weight：416.57300
Appearance:white powder
Synopsis：Spironolactone is a synthetic 17-spironolactone corticosteroid with potassium-sparing diuretic, antihypertensive, and antiandrogen activities.Spironolactone competitively inhibits adrenocortical hormone aldosterone activity in the distal renal tubules, myocardium, and vasculature. This agent may inhibit the pathophysiologic effects of aldosterone produced in excess by various types of malignant and benign tumors.
Structural formula:
Typical Properties
Summary
Spironolactone is a synthetic 17-spironolactone corticosteroid with potassium-sparing diuretic, antihypertensive, and antiandrogen activities.Spironolactone competitively inhibits adrenocortical hormone aldosterone activity in the distal renal tubules, myocardium, and vasculature. This agent may inhibit the pathophysiologic effects of aldosterone produced in excess by various types of malignant and benign tumors.
CAS No.
52-01-7
Formula
C24H32O4S
Molecular Mass
416.57300
Exact Mass
416.20200
PSA
85.74000
Logp
4.85230
IUPAC
S-[(7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxospiro[2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-17,2'-oxolane]-7-yl] ethanethioate
SMILES
CC(=O)S[C@@H]1CC2=CC(=O)CC[C@@]2([C@@H]3[C@@H]1[C@@H]4CC[C@]5([C@]4(CC3)C)CCC(=O)O5)C
Attribute classification
Matter Classification
organic
Category
Auxiliary > Other Auxiliary Agent
API & Intermediate > Urinary System Drugs
API & Intermediate > Urinary System Drugs
Chemical and Physical Properties
Melting Point
207-208 °C
Density
1.24g/cm3
Boiling Point
597ºC
Flash Point
302.3ºC
Appearance
White powder
Acidity and Basicity
neutral reducibility
Export information
HS Code
29322090
Export Rebate
13%
Risk Code
R460-40-36/37/38
Safety Label
T,Xn,Xi
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