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Zhejiang Chemtrue Bio-Pharm Co., Ltd.
Zhejiang Chemtrue Bio-Pharm Co., Ltd.
11 YRS
Gansu, China
Main Products:
2-((2,6-Difluorobenzyl)(Ethoxycarbonyl)Amino)-4-((Dimethylamino)Methyl)-5-(4-Nitrophenyl)Thiophene-3-Carboxylic acid / Crizotinib / Lorlatinib / Relugolix / Sunitinib Malate / Olaparib / 3-Fluoroaniline
Gansu, China
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Lorlatinib / CAS 1454846-35-5
OVERVIEW
Packaging
1 KG/BOTTLE
Lead Time
14-30 days
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DESCRIPTION
Lorlatinib
Chinese name：劳拉替尼
CAS：1454846-35-5
Molecular formula：C21H19FN6O2
Molecular weight：406.41
Structure：
Typical Properties
Summary
Loratinib is a modified ALK inhibitor of crizotinib for the treatment of lung cancer.
CAS No.
1454846-35-5
Formula
C21H19FN6O2
Molecular Mass
406.41300
Exact Mass
406.15500
PSA
110.06000
Logp
3.31978
IUPAC
(16R)-19-amino-13-fluoro-4,8,16-trimethyl-9-oxo-17-oxa-4,5,8,20-tetrazatetracyclo[16.3.1.02,6.010,15]docosa-1(22),2,5,10(15),11,13,18,20-octaene-3-carbonitrile
SMILES
C[CH]1C2=C(C=CC(=C2)F)C(=O)N(CC3=NN(C(=C3C4=CC(=C(N=C4)N)O1)C#N)C)C
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Antineoplastic Agents
Chemical and Physical Properties
Density
1.42±0.1 g/cm3(Predicted)
Boiling Point
675.0±55.0 °C(Predicted)
Appearance
white solid powder
Export information
HS Code
0.0
UN No.
0.0
DG-Class
0.0
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