On Chemball

My Chemball

As Supplier

My RFQ Manage Products

As Buyer

My RFQ Post RFQ

My Account

+86-571-8627 3270

Zhejiang Ruibang Laboratories

68 YRS

Zhejiang, China

CNY 90 Million

55278 m²

100-500 people

Main Products: Mupirocin / Calcium Gluconate / Potassium Gluconate / Cyclosporin A / Zinc Gluconate / Ferrous Gluconate Dihydrate / Magnesium Gluconate / Mupirocin Calcium, Reference Spectrum Ep Standard / Fusidic Acid

Zhejiang, China

Contact Supplier

Home Company Profile Contact Us Post Buying Request

Fusidic Acid / CAS 6990-06-3

OVERVIEW

Packaging

25 KG/Fibre Drum

Lead Time

14-30 days

REQUEST A QUOTATION

Submit

Get Free Samples

Less than 1KG required

DESCRIPTION

Fusidic Acid

1、Nomenclature

English name：Fusidic Acid

2、Structural formula

Molecular

Structure

结构式

Molecular formula：C₃₁H₄₈O₆·1/2 H₂O

Molecular weight：525.7

CAS No.：6990-06-3

3、Mechanism and clinical use:

Fusidic Acid was extracted in 1962 for the first time by the Danish LEO Pharma from the fermentation broth of Fusidium coccineum. It is a narrow-spectrum, high-efficiency and anti gram-positive bacteria antibiotic widely used in foreign countries. Fusidic Acid, as a typical high efficiency antibiotic, although has been widely used in foreign countries for more than 30 years (few used in domestic clinical), still keeps relatively strong antibacterial activity and very low resistance to most staphylococcus strain, more and more receives people’s attention, and becomes new selection of anti resistant staphylococcus aureus (MRSA).

Fusidic Acid is an antibiotic, mainly used for treatment of infections incurred by all kinds of sensitive bacteria, especially by staphylococcus, such as osteomyelitis, sepsis, endocarditis; repeated infections of cystic fibrosis, pneumonia, skin and soft tissue; and infections of surgery and trauma, etc.

Typical Properties

Fusidic acid is a kind of fusulinic acid antibiotic with steroidal skeleton. Its chemical structure is similar to that of cephalosporin P, but not a hormone. It is produced by fusidium coccineum or some Cephalosporium spp in fungi. Its antibacterial spectrum is narrow, similar to that of neomycin. It has obvious effect on Bacteroides fragilis, Streptococcus, streptococcus, Streptococcus, Streptococcus, Streptococcus, Streptococcus, Streptococcus The effect of Streptococcus pneumoniae is weak. Its mechanism of action is to inhibit the protein synthesis of bacteria and play an antibacterial or bactericidal role. In vitro, staphylococcus is easy to develop drug resistance to this product, and there is no cross resistance between bacteria and other anti infective drugs. Clinically, fusidic acid is used for osteomyelitis or skin and soft tissue infection caused by sensitive bacteria. It can also be used for other deep infection, such as sepsis, pneumonia, endocarditis, etc.

CAS No.

6990-06-3

Formula

C31H48O6

Molecular Mass

516.70900

Exact Mass

516.34500

PSA

104.06000

Logp

5.66610

IUPAC

(2Z)-2-[(3R,4S,5S,8S,9S,10S,11R,13R,14S,16S)-16-acetyloxy-3,11-dihydroxy-4,8,10,14-tetramethyl-2,3,4,5,6,7,9,11,12,13,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ylidene]-6-methylhept-5-enoic acid

SMILES

CC1C2CCC3(C(C2(CCC1O)C)C(CC4C3(CC(C4=C(CCC=C(C)C)C(=O)O)OC(=O)C)C)O)C

Matter Classification

organic

GET SAMPLE