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Zhejiang Liaoyuan Pharmaceutical Co.,Ltd.

30 YRS

Zhejiang, China

CNY 28.1 Million

123876 m²

500-1000 people

Main Products: Mirtazapine / Rivaroxaban / Pradaxa / Clopidogrel Bisulfate / Moxifloxacin Intermediate / 2-Thiophene Ethanol / 2-Thiophene Ethylamine

Zhejiang, China

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Dabigatran Etexilate / CAS 211915-06-9

OVERVIEW

Packaging

25 KG/Fibre Drum

Lead Time

14-30 days

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DESCRIPTION

Dabigatran Etexilate

Category	API
Product Name	Dabigatran etexilate
Structure
CAS No.	211915-06-9

Typical Properties

Dabigatran ester is a new synthetic direct thrombin inhibitor. It is the precursor of dabigatran and belongs to non peptide thrombin inhibitor. After oral absorption through gastrointestinal tract, it is transformed into dabigatran with direct anticoagulant activity in vivo. Dabigatran binds to the fibrin specific binding site of thrombin and prevents the cleavage of fibrinogen into fibrin, thus blocking the final step of coagulation waterfall network and thrombosis. Dabigatran can dissociate from fibrin thrombin conjugate and play a reversible anticoagulant effect

CAS No.

211915-06-9

Formula

C34H41N7O5

Molecular Mass

627.73300

Exact Mass

627.31700

PSA

154.03000

Logp

6.37590

IUPAC

ethyl 3-[[2-[[4-[(E)-N'-hexoxycarbonylcarbamimidoyl]anilino]methyl]-1-methylbenzimidazole-5-carbonyl]-pyridin-2-ylamino]propanoate

SMILES

CCCCCCOC(=O)/N=C(\C1=CC=C(C=C1)NCC2=NC3=C(N2C)C=CC(=C3)C(=O)N(CCC(=O)OCC)C4=CC=CC=N4)/N

Matter Classification

organic

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