Pharmacopoeia name: Crosslinked polyvinylketone, Crospovidonum (USP), Crospovidone (EP)
Chemical name: cross-linked polyethylene pyrrolidone
INCI/CTFA:Insoluble PVP
CAS numbers: 9003-39-8, 25249-54-1
Product Description and Properties: White or nearly white powder with hygroscopicity and easy flow, odorless or slightly odorous, insoluble in water, alkali, acid, and commonly used organic solvents, with strong expansion performance and complexing ability with multiple substances.
Quality standard
Item | Pharmaceutical Grade |
PVPP-XL | PVPP-XL-10 | PVPP-SF |
PH value (1% aqueous solution) | 5.0-8.0 | 5.0-8.0 | 5.0-8.0 |
Moisture/% | ≤5.0 | ≤5.0 | ≤5.0 |
Remnant orders/PPM | ≤10 | ≤10 | ≤10 |
Burning residue/% | ≤0.1 | ≤0.1 | ≤0.1 |
Heavy metals/ppm | ≤10 | ≤10 | ≤10 |
Peroxide/PPM | ≤400 | ≤400 | ≤400 |
Arsenic salt/PPM | ≤2 | ≤2 | ≤2 |
Water soluble substance/% | ≤1.0 | ≤1.0 | ≤1.0 |
Nitrogen content/% | 11.0-12.8 | 11.0-12.8 | 11.0-12.8 |
Average particle size μ m | TypeA | TypeB | TypeB |
Main applications and functions
In the field of biomedicine, it can be used as drug disintegrating agents and fillers, drug sustained-release carriers, and hemodialysis membranes.
Packaging and Storage
20KG/cardboard bucket, dark and sealed, stored in a cool and dry place.
Crosslinked polyvinylpyrrolidone (PVPP) is a kind of crosslinked polymer insoluble in water, strong acid, strong base and general organic solvents, which is polymerized by vinyl pyrrolidone monomer under specific conditions. As an important polymer fine chemical product, PVPP has many excellent and unique properties and has been widely used in cosmetics, food, medicine and other fields.
IUPAC
1-ethenylpyrrolidin-2-one