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Hunan Yuxin Pharmaceutical Co., Ltd.
Hunan Yuxin Pharmaceutical Co., Ltd.
22 YRS
Hunan, China
Main Products:
Betamethasone / Budesonide / Clobetasol Propionate / Cyproterone Acetate / Deflazacort / Desonide / Dienogest / Diflorasone / Dutasteride / Estrone / Finasteride / Halobetasol Propionate / Cortisol / Mometasone Furoate / Prednisone
Hunan, China
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Estrone / CAS 53-16-7
OVERVIEW
Packaging
25 KG/Fibre Drum
Lead Time
14-30 days
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DESCRIPTION
Estrone
Chinese Name:雌酚酮
Structural type:
CAS：53-16-7
Molecular formula: C18H22O2
Molecular weight: 270.36
Character: White powder
Usage: It is mainly used for uterine hypoplasia, menstrual disorders and menopausal disorders. It is an intermediate for the synthesis of ethinylestradiol drugs.
Typical Properties
Summary
Estrone is a key intermediate for the synthesis of estrogens and 19 demethyl steroids. Block estradiol and its ethers, estradiol and its esters or estriol and its derivatives synthesized from estrone are the main drugs for women's oral contraceptives or menopausal hormone replacement therapy, respectively.
CAS No.
53-16-7
Formula
C18H22O2
Molecular Mass
270.36600
Exact Mass
270.16200
PSA
37.30000
Logp
3.81740
IUPAC
(8R,9S,13S,14S)-3-hydroxy-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-one
SMILES
CC12CCC3C(C1CCC2=O)CCC4=C3C=CC(=C4)O
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Pharmaceutical Intermediates
API & Intermediate > Hormones And Endocrine Drugs
API & Intermediate > Hormones And Endocrine Drugs
Chemical and Physical Properties
Melting Point
258-260 °C
Density
1.164 g/cm3
Boiling Point
445.2ºC
Flash Point
189.7ºC
Appearance
White crystalline powder
Export information
HS Code
29372390
Export Rebate
13%
Export Formalities
Q
Risk Code
R45; R60; R61
Safety Label
T
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