Chemical name: Cilnidipine
Alias: 3,5-Pyridinedicarboxylic acid,1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,2-methoxyethyl(2E)-3-phenyl-2-propenylester(9CI); 3,5-Pyridinedicarboxylic acid,1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,2-methoxyethyl 3-phenyl-2-propenyl ester,(E)-(±)-;( ±)-FRC 8653;3,5-Pyridinedicarboxylic acid,1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,2-methoxyethyl 3-phenyl-2-propenyl ester,(E)- ;Atelec;Cilacar 10;Cilnidipine;Cinaldipine;Cinalong;FRC 8653;FRG 8653;
Siscard
Molecular formula: C27H28N2O7
Molecular weight: 492.52
CAS Number: 132203-70-4
Purity: HPLC≥99.5%
Melting point: 115.5-116.6 °C
Boiling point: 652.6±55.0 °C | Condition: Press: 760 Torr
Density: 1.240±0.06 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
Acidity coefficient pKa: 2.61±0.70 | Condition: Most Basic Temp: 25 °C
Storage conditions: 2-8°C, dry, protected from light, sealed
Cilnidipine is the third generation dihydropyridine calcium channel blocker, which has a strong blocking effect on L-type and N-type Ca2 + channels. It has good comprehensive antihypertensive effect and anti atherosclerotic effect. It is used for mild, moderate or severe hypertension, heart failure and ischemic heart disease.
IUPAC
3-O-(2-methoxyethyl) 5-O-[(E)-3-phenylprop-2-enyl] 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate
SMILES
CC1=C(C(C(=C(N1)C)C(=O)OCC=CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OCCOC