Quality criteria: USP30 / bp2012 / ep6.0/cpv2015
English Name: phthalylsulphathiazole (P-St)
CAS No.: 85-73-4
Molecular formula: C17H13N3O5S2
MW: 403.43
Structural formula:
Appearance: white or yellowish crystalline powder
Content: ≥ 98.5%
Loss on drying: ≤ 2%
MP: 198-204 ° C
Package specifications: 25 kg / cardboard bucket, Φ thirty-six point five × 1175px
Storage conditions: shade, tight storage
Uses: after hydrolysis in the intestine to free amino groups, it can exert bacteriostatic effect. Spp., broad-spectrum, slow acting bacteriostatic drug. In the large intestine, the antibacterial effect was stronger than that of SG, which exceeded that of SST by 2-4 times. Sulfonamides. For gallinaceous dysentery, gallinaceous dysentery, paratyphoid fever). Is an intestinal anti-inflammatory drug.
Customs Code: 29350090
Phthalic sulfathiazole is a kind of sulfanilamide antibacterial drug, which is similar to sulfamethoxazole and sulfothiazole succinate and has strong effect. It is rarely absorbed by oral administration. It slowly decomposes and releases sulfathiazole in the intestine to play the role of intestinal bacteriostasis. It is clinically used for enteritis, bacillary dysentery and intestinal preoperative preparation. Do not use sulfonamides when allergic. It is a broad-spectrum and slow acting antibacterial drug. It has strong antibacterial effect in large intestine, 2-4 times of SST. It is used for the treatment of avian pullorum, avian pullorum disease, paratyphoid, etc.
IUPAC
2-[[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]carbamoyl]benzoic acid
SMILES
C1=CC=C(C(=C1)C(=O)NC2=CC=C(C=C2)S(=O)(=O)NC3=NC=CS3)C(=O)O