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Zhejiang East-Asia Pharmaceutical Co.,Ltd.
Zhejiang East-Asia Pharmaceutical Co.,Ltd.
26 YRS
Zhejiang, China
Main Products:
Ofloxacin / Levofloxacin Hemihydrate / Levofloxacin Hydrochloride / Trimebutine Maleate Salt / Ketoconazole / Tioconazole / Terbinafine Hydrochloride / Loratadine / Cefaclor
Zhejiang, China
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Terbinafine Hydrochloride / CAS 78628-80-5
OVERVIEW
Packaging
25 KG/Fibre Drum
Lead Time
14-30 days
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DESCRIPTION
Terbinafine Hydrochloride
English name： | Terbinafine Hydrochloride |
Chemical name： | N-[(2E)-6,6-Dimethyl-2-hepten-4-ynyl]-N-methyl-1-naphthalenemethanamine hydrochloride |
Category involved： | bulk pharmaceutical chemicals |
Structural type： |
|
CAS#： | 78628-80-5 |
Molecular formula： | C21H25N•HCl |
Molecular weight： | 327.9 |
Quality standard： | Comply with the standards of CP/EP/USP |
Application： | This product is allylamine broad-spectrum antifungal agents. |
Storage condition： | Room temperature storage, heat proof, moisture proof. |
Packaging specifications： | 20 KG/barrel, cardboard drum, lined with two layers of plastic film. |
Typical Properties
Summary
Terbinafine hydrochloride is a broad-spectrum antifungal drug used in dermatology. It can specifically disturb the late biological decomposition of fungal sterols, selectively inhibit the activity of squalene cyclooxygenase, and block the reaction of squalene epoxidation in the process of fungal cell membrane formation, so as to kill or inhibit fungi. It is suitable for the treatment of skin candidiasis, such as tinea manus, tinea pedis, tinea cruris, tinea corporis and tinea versicolor. It is also the best drug for the treatment of onychomycosis.
CAS No.
78628-80-5
Formula
C21H26ClN
Molecular Mass
327.89100
Exact Mass
327.17500
PSA
3.24000
Logp
5.67930
IUPAC
(E)-N,6,6-trimethyl-N-(naphthalen-1-ylmethyl)hept-2-en-4-yn-1-amine;hydrochloride
SMILES
CC(C)(C)C#CC=CCN(C)CC1=CC=CC2=CC=CC=C21.Cl
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Synthetic Anti Infective Drugs
Chemical and Physical Properties
Melting Point
204-208 °C
Density
1.007 g/cm3
Boiling Point
417.9 ºC
Flash Point
183.7 ºC
Appearance
White crystalline powder
Export information
HS Code
29214990
Export Rebate
13%
UN No.
3077
DG-Class
9
Risk Code
R36/37/38-50/53
Safety Label
Xi,N
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