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Hubei Teyer Pharmaceutical Co., Ltd.

22 YRS

Hubei, China

CNY 10 Million

15984 m²

Less than 50 people

Main Products: Valacyclovir Hydrochloride / Cbz-Valine Ganciclovir / O-Acetyl N-Benzyloxycarbonyl Valganciclovir / Ganciclovir Mono-O-Acetate / Mono Benzyl Ganciclovir / Benzyl Dipropionate / Triacetyl Methoxyglycerin / 1,3-Dichloro-2-(Acetoxymethoxy)Propane / Cbz-Valaciclovir / Ganciclovir / Ganciclovir Sodium / Valganciclovir Hydrochloride / Vandetanib

Hubei, China

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Vandetanib / CAS 443913-73-3

OVERVIEW

Packaging

25 KG/Fibre Drum

Lead Time

14-30 days

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DESCRIPTION

Vandetanib

English Name: vandetanib

CAS No.: 443913-73-3

Molecular formula: C22H24BrFN4O2

Molecular weight: 475.35

EINECS No.: 669-841-4

Melting point: 240-243 º C

Boiling point: 538.2 ± 50.0 ° C (predicted)

Application: vandetanib is a once daily oral inhibitor of vascular endothelial growth factor receptor 2 and epidermal growth factor receptor kinase activity.

Typical Properties

Vandetanib (INN, trade name Caprelsa) is an anti-cancer drug that is used for the treatment of certain tumours of the thyroid gland. It acts as a kinase inhibitor of a number of cell receptors, mainly the vascular endothelial growth factor receptor (VEGFR), the epidermal growth factor receptor (EGFR), and the RET-tyrosine kinase. The drug was developed by AstraZeneca.

CAS No.

443913-73-3

Formula

C22H24BrFN4O2

Molecular Mass

475.35400

Exact Mass

474.10700

PSA

59.51000

Logp

5.01510

IUPAC

N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4-amine

SMILES

CN1CCC(CC1)COC2=C(C=C3C(=C2)N=CN=C3NC4=C(C=C(C=C4)Br)F)OC

Matter Classification

organic

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