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Cheng Du Ya Zhong Bio-Pharmaceutical Co., Ltd.
Cheng Du Ya Zhong Bio-Pharmaceutical Co., Ltd.
22 YRS
Sichuan, China
Main Products:
Diosmin / Vitamin D2 / Ergosterol / [(3S,5R)-5-(2,4-Difluorophenyl)-5-(1,2,4-Triazol-1-Ylmethyl)Oxolan-3-Yl]Methyl 4-Methylbenzenesulfonate / [(3S,5R)-5-(2,4-Difluorophenyl)-5-(1,2,4-Triazol-1-Ylmethyl)Tetra Hydrofuran-3-Yl]Methyl 4-Chlorobenzenesulfonate / 2-[(1S,2S)-1-Ethyl-2-Bezyloxypropyl]-2,4-Dihydro-4-[4-[4-(4-Hydroxyphenyl)-1-Piperazinyl]Phenyl]- 3H-1,2,4-Triazol-3-One
Sichuan, China
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Diosmin
Vitamin D2
Ergosterol
[(3S,5R)-5-(2,4-Difluorophenyl)-5-(1,2,4-Triazol-1-Ylmethyl)Oxolan-3-Yl]Methyl 4-Methylbenzenesulfonate
[(3S,5R)-5-(2,4-Difluorophenyl)-5-(1,2,4-Triazol-1-Ylmethyl)Tetra Hydrofuran-3-Yl]Methyl 4-Chlorobenzenesulfonate
2-[(1S,2S)-1-Ethyl-2-Bezyloxypropyl]-2,4-Dihydro-4-[4-[4-(4-Hydroxyphenyl)-1-Piperazinyl]Phenyl]- 3H-1,2,4-Triazol-3-One
Diosmin / CAS 520-27-4
OVERVIEW
Packaging
25 KG/Fibre Drum
Lead Time
14-30 days
Max Capacity
800 MT/Year
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DESCRIPTION
Diosmin
CAS No.: 520-27-4
Molecular structure: 
Specification：CP/EP ; Micronized powder
Source: Citrus extract
Function: It is an oral phlebotropic drug used in the treatment of venous disease, including chronic venous insufficiency (CVI) spider and varicose veins, leg swelling (edema), stasis dermatitis and venous ulcers. It is also used as a stand-alone or surgical adjunctive therapy in hemorrhoidal disease (HD).
There are extensive clinical trials that show diosmin improves all stages of venous disease including venous ulcers and improves quality of life.
Typical Properties
Summary
It has vitamin P like effect, vitamin C2 like effect and anti-inflammatory effect. The effect of rutin is better than Rutin in the treatment of capillary fragility.
CAS No.
520-27-4
Formula
C28H32O15
Molecular Mass
608.54500
Exact Mass
608.17400
PSA
238.20000
Logp
-1.08970
IUPAC
5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxychromen-4-one
SMILES
CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=CC(=C4C(=C3)OC(=CC4=O)C5=CC(=C(C=C5)OC)O)O)O)O)O)O)O)O
Attribute classification
Matter Classification
organic
Category
Plant and Other Extracts > Herbal Drugs Preparation
API & Intermediate > Blood System Drugs
API & Intermediate > Blood System Drugs
Chemical and Physical Properties
Melting Point
277-278°C
Density
1.68 g/cm3
Boiling Point
926.8ºC
Flash Point
305.2ºC
Appearance
neat
Acidity and Basicity
reducibility acidness
Export information
HS Code
29329990
Export Rebate
13%
Risk Code
R36/37/38
Safety Label
Xi
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