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Luohe Chief Pharmaceutical Co., Ltd.
Luohe Chief Pharmaceutical Co., Ltd.
11 YRS
Henan, China
Main Products:
Rifaximin / Rifamycin S / Rifampicin / Rifabutin / Rifamycin Sodium Salt / Rifapentine / L-2-Aminobutyric acid
Henan, China
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Rifabutin / CAS 72559-06-9
OVERVIEW
Packaging
25 KG/Plastic Drum
Lead Time
14-30 days
Max Capacity
20 MT/Year
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DESCRIPTION
Rifabutin
Chinese name：利福布汀
CAS NO：72559-06-9
Molecular weight：847
Molecular formula：C46H62N4O11
Structural formula：
Appearance：Amorphous red-violet powder
Application：an antibiotic used to treat tuberculosis and prevent and treat Mycobacterial complexes
Typical Properties
Summary
Rifabutin is a kind of semi synthetic rifamycin, which has good fat solubility and can be widely distributed in tissues and cells. It can effectively inhibit the DNA dependent RNA polymerase of bacteria, thereby inhibiting and killing bacteria. It is suitable for treating all types of tuberculosis caused by Mycobacterium tuberculosis combined with other anti tuberculosis drugs, and can also be used for the treatment of non tuberculous mycobacteria infection. This product is also suitable for preventing the spread of MAC in patients with advanced HIV infection.
CAS No.
72559-06-9
Formula
C46H62N4O11
Molecular Mass
847.00500
Exact Mass
846.44200
PSA
205.55000
Logp
4.64680
IUPAC
[(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,32-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-1'-(2-methylpropyl)-6,23-dioxospiro[8,33-dioxa-24,27,29-triazapentacyclo[23.6.1.14,7.05,31.026,30]tritriaconta-1(32),2,4,9,19,21,24,26,30-nonaene-28,4'-piperidine]-13-yl] acetate
SMILES
CC1C=CC=C(C(=O)N=C2C(=C3C(=C4C2=NC5(N4)CCN(CC5)CC(C)C)C6=C(C(=C3O)C)OC(C6=O)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)O)C
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Antibiotics
Chemical and Physical Properties
Melting Point
169-171 ºC
Density
1.339 g/cm3
Boiling Point
969.589 ºC
Flash Point
540.188 ºC
Appearance
Red to violet crystalline powder
Acidity and Basicity
alkalinity acidness
Export information
HS Code
29419030
Export Rebate
13%
Export Formalities
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