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CHANGZHOU REDSUN PHARMACEUTICALS CO.,LTD
CHANGZHOU REDSUN PHARMACEUTICALS CO.,LTD
31 YRS
Jiangsu, China
Main Products:
Furosemide / Moxifloxacin Hydrochloride / Sulbactam / Aliskiren / Meldrum'S Acid / Cefotetan / Raltegravir / Tazobactam Acid
Jiangsu, China
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Aliskiren / CAS 173334-57-1
OVERVIEW
Packaging
25 KG/Fibre Drum
Lead Time
14-30 days
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DESCRIPTION
English Name: aliskiren
CAS No.: 173334-57-1
Molecular formula: C30H53N3O6
Structural type:
Molecular weight: 551.76
EINECS No.: 605-672-4
Overview: aliskiren is a second-generation renin inhibitor, which acts on the first rate limiting step of renin angiotensin aldosterone system (RAS). At present, all research data show that alikelen antihypertensive treatment has good safety and effectiveness, less side effects, long half-life and convenient to take once a day. It has entered phase III clinical practice and is expected to become the first oral renin inhibitor for the treatment of hypertension, other cardiovascular diseases and nephropathy.
Typical Properties
Summary
Alikelen is a second-generation renin inhibitor, which acts on the first rate limiting step of renin angiotensin aldosterone system (RAS). At present, all research data show that alikelen antihypertensive treatment has good safety and effectiveness, less side effects, long half-life and convenient to take once a day. It has entered phase III clinical practice and is expected to become the first oral renin inhibitor for the treatment of hypertension, other cardiovascular diseases and nephropathy.
CAS No.
173334-57-1
Formula
C30H53N3O6
Molecular Mass
551.75800
Exact Mass
551.39300
PSA
146.13000
Logp
5.08500
IUPAC
(2S,4S,5S,7S)-5-amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-4-hydroxy-7-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-8-methyl-2-propan-2-ylnonanamide
SMILES
CC(C)[C@@H](CC1=CC(=C(C=C1)OC)OCCCOC)C[C@@H]([C@H](C[C@@H](C(C)C)C(=O)NCC(C)(C)C(=O)N)O)N.C(=C/C(=O)O)\C(=O)O
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Pharmaceutical Raw Materials
Chemical and Physical Properties
Melting Point
98-99 °C
Density
1.067 g/cm3
Boiling Point
748.4ºC
Flash Point
406.4ºC
Appearance
solid
Export information
HS Code
29242990
Export Rebate
13%
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