On Chemball
My Chemball
+86-571-8627 3270
Jiangxi Chenyang Pharmaceutical Co.,Ltd.
Jiangxi Chenyang Pharmaceutical Co.,Ltd.
16 YRS
Jiangxi, China
Main Products:
Gatifloxacin Cyclization Ester / Gatifloxacin / 1-Cyclopropyl-6,7-Difluoro-1,4-Dihydro-8-Methoxy-4-Oxo-3-Quinolinecarboxylic Acid / Praziquantel
Jiangxi, China
Send Email
Sending...
Thank You！
Your requirement has been sent, we will contact you quickly!
Sent Failed！
Try again!
Gatifloxacin / CAS 112811-59-3
OVERVIEW
Packaging
25 KG/Fibre Drum
Lead Time
14-30 days
REQUEST A QUOTATION
SubmitGet Free Samples
Less than 1KG required
DESCRIPTION
Gatifloxacin
Product name | Gatifloxacin |
Alias | 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid |
CAS | 112811-59-3 |
Structure |
|
Molecular Formula | C19H22FN3O4 |
Molecular Weight | 375.40 |
Typical Properties
Summary
Gatifloxacin is the fourth generation of fluoroquinolones, which belongs to 8-methoxyfluoroquinolones racemic compound. It has broad-spectrum anti gram negative and positive microorganisms and activity. It was first developed by Xinglin Pharmaceutical Co., Ltd. of Japan. Its R - and s-enantiomers have the same antibacterial activity. It can inhibit bacterial DNA replication by inhibiting DNA gyrase and topoisomerase IV It plays an important role in the process of transcription and repair. It has strong antibacterial effect on a variety of bacteria, and has good curative effect on respiratory and reproductive system infections. It is one of the representatives of "respiratory fluoroquinolones" which have been growing rapidly in recent years. It is mainly used for the treatment of various mild and moderate infectious diseases caused by sensitive pathogens, including chronic bronchitis, acute sinusitis, community-acquired pneumonia, simple urinary tract infection (cystitis), complicated urinary tract infection, cystitis, acute pyelonephritis and infection of urethra, cervix and rectum caused by Neisseria gonorrhoeae.
CAS No.
112811-59-3
Formula
C19H22FN3O4
Molecular Mass
375.39400
Exact Mass
375.15900
PSA
83.80000
Logp
2.37420
IUPAC
1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
SMILES
CC1CN(CCN1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Synthetic Anti Infective Drugs
Chemical and Physical Properties
Melting Point
162°C
Density
1.386 g/cm3
Boiling Point
607.8ºC
Flash Point
321.4ºC
Appearance
White powder
Export information
HS Code
29335990
Export Rebate
13%
Risk Code
R20/21/22
Safety Label
Xn
GET SAMPLE
Submit- Overview
- Descriptions
- Sample