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Yabao Pharmaceutical Group Co., Ltd.

46 YRS

Shanxi, China

CNY 770 Million

2997000 m²

Over 1000 people

Main Products: Aniracetam / Troxerutin / Nimodipine / Dihydralazine Sulphate / Magnesium Trisilicate

Shanxi, China

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Nimodipine / CAS 66085-59-4

OVERVIEW

Packaging

10 KG/Fibre Drum

Lead Time

14-30 days

Max Capacity

30 MT/Year

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DESCRIPTION

Nimodipine

Drug name: Nimodipine

Dosage form: API

Specification: 10kg / barrel

Registration No.: Y20190004586

CDE status: A

Purpose: cerebral vasospasm after subarachnoid hemorrhage and improvement of blood circulation in the recovery period of acute cerebrovascular disease. Pulsatile headache

CAS：66085-59-4

Molecular formula: C21H26N2O7

Typical Properties

Nimodipine is the latest generation of 1,4-dihydropyridine calcium channel antagonist, namely calcium blocker. It can inhibit calcium influx outside vascular smooth muscle cells, protect cerebral arteries in vitro or in vivo or ischemic cerebral arteries, and significantly improve cerebral blood flow, It can effectively prevent and treat ischemic damage of brain tissue caused by cerebral vasospasm caused by subarachnoid hemorrhage, migraine and sudden deafness. It can also be used in mild and moderate hypertension. It can effectively regulate calcium in the body to maintain normal physiological function, especially for cerebral vessels, and can combine with specific receptor of central nerve. It can selectively dilate the cerebral blood vessels at the appropriate dose without affecting the peripheral blood vessels. Increasing the dose also has a good effect on hypertension.

CAS No.

66085-59-4

Formula

C21H26N2O7

Molecular Mass

418.44000

Exact Mass

418.17400

PSA

119.68000

Logp

3.82280

IUPAC

3-O-(2-methoxyethyl) 5-O-propan-2-yl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

SMILES

CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=CC(=CC=C2)[N+](=O)[O-])C(=O)OCCOC

Matter Classification

organic

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