Benzophenone
Application of benzophenone:
There are many varieties of benzophenone series products, which have been widely used in medicine, pesticides, dyes, plastics, coatings, daily chemicals, electronic chemicals and other fields. In many fields, it is mainly used as photoinitiator, ultraviolet absorber and pharmaceutical intermediate.
1. Photoinitiator
As an environmentally friendly green technology, light-curing technology has developed vigorously in recent years and has been widely used in coatings, inks, adhesives, electronic devices, optical fiber materials and other industries. The photoinitiator is the main component of the photocuring system, which plays a decisive role in the sensitivity of the curing system. Photoinitiators are divided into three categories: homolytic fragmentation, hydrogen transfer and cationic. Benzophenone-based hydrogen transfer photoinitiators are better than monomers and prepolymers due to their high quantum efficiency, fast curing speed, absorption spectrum matching the range of the irradiation light source, good thermal stability, and no dark reaction. good compatibility. The photo-curing film has no yellowing or discoloration, is cheap and safe to use, so it has become the photoinitiator with the largest output at present.
2. UV Absorber
Benzophenone UV absorbers are currently the most widely used and produced UV absorbers. In addition to absorbing ultraviolet light of 290-400nm, it also absorbs part of visible light. It is widely used in plastics, inks, paints, cosmetics and other industries because of its good compatibility with other materials.
3. Pharmaceutical intermediates
Benzophenone series products are the intermediates of many medicines. For example, benzophenone is the intermediate of anti-suspension drug diphenhydramine, 2-amino-5-chlorobenzophenone is the intermediate of tranquilizer medicine, 4- Chlorobenzophenone is used in the production of antiallergic drugs such as Anqimin. For example, ketoprofen, a highly effective anti-inflammatory and analgesic drug, is obtained from m-methylbenzophenone through bromination, cyanation, hydrolysis and methylation.
Basic information of benzophenone:
CAS: 119-61-9
Molecular formula: C13H10O
Molecular weight: 182.21800
Structural formula:
Physicochemical properties of benzophenone:
Appearance: white flake solid
Melting point: 47-51 °C
Density: 1.11 g/cm3
Boiling point: 305 °C
Flash point: >230 °F
Benzophenone is colorless prismatic crystal with sweet and rose flavor. It is soluble in organic solvents and monomers such as ethanol, ether, chloroform, and insoluble in water. It is a free radical photoinitiator. It is mainly used in free radical UV curing systems, such as coatings, inks, adhesives, etc. it is also an intermediate of organic pigments, pharmaceuticals, spices, and pesticides. In the pharmaceutical industry, it is mainly used to produce dicyclohexyl piperidine, benzotropine hydrobromide, diphenhydramine hydrochloride, etc. This product is also a styrene polymerization inhibitor and spice setting agent. It can give spices sweet flavor and is widely used in perfumes and soap flavors.
SMILES
C1=CC=C(C=C1)C(=O)C2=CC=CC=C2