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Hubei Honch Pharmaceutical CO.,Ltd.
Hubei Honch Pharmaceutical CO.,Ltd.
17 YRS
Hubei, China
Main Products:
Vinorelbine L-Tartrate / Vincristine Sulfate / Vincaleukoblastine Sulfate / Mitomycin C / Bortezomib / Epothilone B / Ixabepilone / Staurosporine / Midostaurin / Melphalan Hydrochloride / Lufenuron / Nitenpyram / Doramectin / Milbemite
Hubei, China
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Mitomycin / CAS 50-07-7
OVERVIEW
Lead Time
14-30 days
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DESCRIPTION
Mitomycin
CAS:50-07-7
Molecular formula：C15H18N4O5
Molecular weight：334.32
Appearance:Dark blue gray crystalline powder
Purpose：Mitomycin is a methylazirinopyrroloindoledione antineoplastic antibiotic isolated from the bacterium Streptomyces caespitosus and other Streptomyces bacterial species. Bioreduced mitomycin C generates oxygen radicals, alkylates DNA, and produces interstrand DNA cross-links, thereby inhibiting DNA synthesis. Preferentially toxic to hypoxic cells, mitomycin C also inhibits RNA and protein synthesis at high concentrations.
Structural formula:
Typical Properties
Summary
Mitomycin is a methylazirinopyrroloindoledione antineoplastic antibiotic isolated from the bacterium Streptomyces caespitosus and other Streptomyces bacterial species. Bioreduced mitomycin C generates oxygen radicals, alkylates DNA, and produces interstrand DNA cross-links, thereby inhibiting DNA synthesis. Preferentially toxic to hypoxic cells, mitomycin C also inhibits RNA and protein synthesis at high concentrations.
CAS No.
50-07-7
Formula
C15H18N4O5
Molecular Mass
334.32700
Exact Mass
334.12800
PSA
146.89000
Logp
0.01610
IUPAC
[(4S,6S,7R,8S)-11-amino-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate
SMILES
CC1=C(C(=O)C2=C(C1=O)N3CC4C(C3(C2COC(=O)N)OC)N4)N
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Antineoplastic Agents
Chemical and Physical Properties
Melting Point
360 °C
Density
1.56g/cm3
Boiling Point
581.8ºC
Flash Point
305.6ºC
Appearance
Dark blue gray crystalline powder
Acidity and Basicity
reducibility alkalinity
Export information
HS Code
29419090
Export Rebate
13%
Export Formalities
Q
UN No.
3462
DG-Class
6.1
Risk Code
R25-40-22-45-26/27/28
Safety Label
T，Xn,T+
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