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Zhongshuai Pharmaceutical Sci&tech CO.,Ltd.
Zhongshuai Pharmaceutical Sci&tech CO.,Ltd.
23 YRS
Henan, China
Main Products:
Acetazolamide / Guanfacine Hydrochloride / Dexmethylphenidate Hydrochloride / Memantine Hydrochloride
Henan, China
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Guanfacine Hydrochloride / CAS 29110-48-3
OVERVIEW
Packaging
25 KG/Fibre Drum
Lead Time
14-30 days
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DESCRIPTION
Guanfacine Hydrochloride
CAS:29110-48-3
Molecular formula：C9H10Cl3N3O
Molecular weight：282.55400
Appearance:White to grayish white crystalline powder
Synopsis:Guanfacine hydrochloride is a central antihypertensive drug, and its pharmacological effect is similar to clonidine. It is a kind of center α 2 receptor activator, activation center α 2 receptors, reduce peripheral sympathetic activity, resulting in decreased blood pressure. The antihypertensive effect of this drug is weaker than that of clonidine. Therefore, the dose is 7 ~ 10 times higher than that of clonidine, and the sedative effect of pivot nervous system is also weak, and the action site may be different from that of clonidine.
Structural formula:
Typical Properties
Summary
Guanfacine hydrochloride is a central antihypertensive drug, and its pharmacological effect is similar to clonidine. It is a kind of center α 2 receptor activator, activation center α 2 receptors, reduce peripheral sympathetic activity, resulting in decreased blood pressure. The antihypertensive effect of this drug is weaker than that of clonidine. Therefore, the dose is 7 ~ 10 times higher than that of clonidine, and the sedative effect of pivot nervous system is also weak, and the action site may be different from that of clonidine.
CAS No.
29110-48-3
Formula
C9H10Cl3N3O
Molecular Mass
282.55400
Exact Mass
280.98900
PSA
78.97000
Logp
3.53850
IUPAC
N-(diaminomethylidene)-2-(2,6-dichlorophenyl)acetamide;hydrochloride
SMILES
C1=CC(=C(C(=C1)Cl)CC(=O)N=C(N)N)Cl.Cl
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Nervous System Drugs
Chemical and Physical Properties
Melting Point
215-217℃
Appearance
white powder
Export information
HS Code
29252900
Export Rebate
13%
UN No.
3249
DG-Class
6.1(b)
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