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Hubei Xunda Pharmaceutical Co.,Ltd.

22 YRS

Hubei, China

CNY 46 Million

190476 m²

500-1000 people

Main Products: Ketoprofen / 2-(3-Benzoylphenyl)Propionitrile / Loxoprofen Sodium / [(2R,3S)-3-Methyloxiran-2-Yl]Phosphonic Acid,(1R)-1-Phenylethanamine / Fosfomycin Calcium / 2,3,4,5-Tetrafluorobenzoyl Chloride / 4-(4-Fluorophenyl)-6-Isopropyl-2-[(N-Methyl-N-Methylsufonyl)Amino]Pyrimidine-5-yl-Methanol / N-[5-(Diphenylphosphorylmethyl)-4-(4-Fluorophenyl)-6-Propan-2-Ylpyrimidin-2-Yl]-N-Methylmethanesulfonamide / N-[4-(4-Fluorophenyl)-5-Formyl-6-(1-Methylethyl)-2-Pyrimidinyl]-N-Methyl-Methanesulfonamide

Hubei, China

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Intermediate of Rosuvastatin: Z-9 / CAS 289042-10-0

OVERVIEW

Packaging

25 KG/Fibre Drum

Lead Time

14-30 days

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DESCRIPTION

Intermediate of Rosuvastatin: Z-9

Chemical name: 4-(4-Fluorophenyl)-5-(diphenylphosphinyl)methyl-6-isopropyl-2-[(N-methyl-n-methylsulfonyl)amino]pyrimidine

CAS：289042-10-0

Structural formula:

Molecular formula: C₂₈H₂₉FN₃O₃PS

Molecular weight: 537.58

Typical Properties

This product is the intermediate of rosuvastatin calcium. Rosuvastatin calcium is a selective 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor. By inhibiting HMG CoA reductase, rosuvastatin calcium can reduce the synthesis and storage of cholesterol in hepatocytes, thereby reducing the levels of total cholesterol and low density lipoprotein cholesterol in blood.

CAS No.

289042-10-0

Formula

C28H29FN3O3PS

Molecular Mass

537.58500

Exact Mass

537.16500

PSA

98.42000

Logp

6.39680

IUPAC

N-[5-(diphenylphosphorylmethyl)-4-(4-fluorophenyl)-6-propan-2-ylpyrimidin-2-yl]-N-methylmethanesulfonamide

SMILES

CC(C)C1=NC(=NC(=C1CP(=O)(C2=CC=CC=C2)C3=CC=CC=C3)C4=CC=C(C=C4)F)N(C)S(=O)(=O)C

Matter Classification

organic

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