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Jiangxi Synergy Pharmaceutical Co.,Ltd.
Jiangxi Synergy Pharmaceutical Co.,Ltd.
20 YRS
Jiangxi, China
Main Products:
Gabapentin / Celecoxib / Rebamipide / Aceclofenac / Candesartan Cilexetil / Rivaroxaban / Ticagrelor / Venlafaxine Hydrochloride / Atazanavir Sulfate / 2-((4-Cyanophenyl)Amino)Acetic Acid
Jiangxi, China
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Candesartan Cilexetil / CAS 145040-37-5
OVERVIEW
Packaging
10 KG/Fibre Drum; 15 KG/Fibre Drum
Lead Time
14-30 days
Max Capacity
25 MT/Year
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DESCRIPTION
Candesartan Cilexetil
CAS number: 145040-37-5
Molecular formula: C33H34N6O6
Molecular weight: 610.67
Product Standard: In House/EP7.3/USP35/JP16/BP2012
Packaging and storage: 15,10kg/drum, inner packaging: two-layer polyethylene film bag, outer packaging: full paper drum.
Store at low temperature and away from light. The product re-inspection period is two years
Typical Properties
Summary
Candesartan axetil was rapidly decomposed into the active metabolite candesartan in vivo. Candesartan is an angiotensin Ⅱ at receptor antagonist. It antagonizes the contraction of angiotensin Ⅱ by binding to at receptor of vascular smooth muscle, so as to reduce peripheral vascular resistance. It is suitable for essential hypertension.
CAS No.
145040-37-5
Formula
C33H34N6O6
Molecular Mass
610.66000
Exact Mass
610.25400
PSA
143.34000
Logp
6.31910
IUPAC
1-cyclohexyloxycarbonyloxyethyl 2-ethoxy-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]benzimidazole-4-carboxylate
SMILES
CCOC1=NC2=CC=CC(=C2N1CC3=CC=C(C=C3)C4=CC=CC=C4C5=NNN=N5)C(=O)OC(C)OC(=O)OC6CCCCC6
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Blood System Drugs
Chemical and Physical Properties
Melting Point
168-170ºC
Density
1.37±0.1 g/cm3(Predicted)
Boiling Point
843.3±75.0 °C(Predicted)
Flash Point
463.8ºC
Appearance
white to beige powder
Export information
HS Code
29339900
Export Rebate
13%
UN No.
0.0
DG-Class
0.0
Risk Code
R20/21/22
Safety Label
Xn,N,T
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