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Junye Pharmaceutical Co., Ltd

26 YRS

Zhejiang, China

CNY 97.5 Million

500-1000 people

Main Products: Drospirenone / Norethisterone / Norethindrone Acetate / Norethisterone Enanthate / Progesterone / Ulipristal Acetate / Dexamethasone / Dexamethasone Sodium Phosphate / Abiraterone / Finasteride / Hydrocortisone Acetate / Hydrocortisone / Deflazacort / β-Estradiol / Oestradiol 17-Heptanoate / Estradiol Valerate / Medroxyprogesterone Acetate / Hydroxyprogesterone Caproate / 17α-Ethynylestradiol / Estriol / Prednisolone / Prednisolone Acetate / Trilostane / Altrenogest / Eplerenone / Tibolone / Flumethasone / Fulvestrant / Oxandrolone

Zhejiang, China

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Norethisterone / CAS 68-22-4

OVERVIEW

Uses

Norethindrone Acetate Norethindrone Acetate

Packaging

25 KG/Fibre Drum

Lead Time

14-30 days

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DESCRIPTION

Norethisterone

CAS:68-22-4

Molecular formula：C20H26O2

Molecular weight：298.41900

Appearance:white crystal

Synopsis：Norethisterone, a derivative of 19 demethyltestosterone, is an oral progesterone. Its progesterone activity is 4 times higher than that of progesterone, and its estrogen and androgen activities are weak. It can inhibit the secretion of hypothalamic luteinizing releasing hormone (LHRH). By stimulating the anterior pituitary, it can reduce the sensitivity of the body to LHRH, so as to block the release of gonadotropin and inhibit ovulation. After oral administration of this product for 0.5 ~ 4 hours, the blood concentration can reach the peak, and the half-life is 5 ~ 14 hours. Most of the metabolites are discharged from the body through the kidney.

Structural formula:

Typical Properties

Norethisterone, a derivative of 19 demethyltestosterone, is an oral progesterone. Its progesterone activity is 4 times higher than that of progesterone, and its estrogen and androgen activities are weak. It can inhibit the secretion of hypothalamic luteinizing releasing hormone (LHRH). By stimulating the anterior pituitary, it can reduce the sensitivity of the body to LHRH, so as to block the release of gonadotropin and inhibit ovulation. After oral administration of this product for 0.5 ~ 4 hours, the blood concentration can reach the peak, and the half-life is 5 ~ 14 hours. Most of the metabolites are discharged from the body through the kidney.

CAS No.

68-22-4

Formula

C20H26O2

Molecular Mass

298.41900

Exact Mass

298.19300

PSA

37.30000

Logp

3.49250

IUPAC

(8R,9S,10R,13S,14S,17R)-17-ethynyl-17-hydroxy-13-methyl-1,2,6,7,8,9,10,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-3-one

SMILES

CC12CCC3C(C1CCC2(C#C)O)CCC4=CC(=O)CCC34

Matter Classification

organic

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