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Baiyin Yier Fine Chemical Co., Ltd.
Baiyin Yier Fine Chemical Co., Ltd.
9 YRS
Gansu, China
Main Products:
Pioglitazone Hydrochloride / 1,2,6,7-Tetrahydrocyclopenta[E][1]Benzofuran-8-One / Bendamustine HCl / Flupirtine Maleate / Iloperidone / Paliperidone
Gansu, China
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Bendamustine Hydrochloride / CAS 3543-75-7
OVERVIEW
Packaging
25 KG/Fibre Drum
Lead Time
14-30 days
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DESCRIPTION
Name of Product：Bendamustine HCl
CAS No：3543-75-7
Name of product：
Quality standard：
Structural formula：
Typical Properties
Summary
Bendamostine hydrochloride was first developed by ozegowski and his colleagues in the microbial experimental Association in Jena, Germany in the early 1860s. The initial purpose was to connect an alkylated nitrogen mustard (a non effective alkylating agent) with a purine and an amino acid. Compared with nitrogen mustard phenylbutyrate, the main advantage of the newly synthesized compound is its water solubility. It was widely used, but until the end of the cold war, the drug has been carried out in Europe for many single drugs or other drugs for the treatment of various hematological malignancies or non Hodgkin's lymphoma, multiple myeloma, CLL and breast cancer. The clinical effect is very significant, significantly reducing the rate of recurrence and mortality, and has little side effects. Good security. So far, bendamostine hydrochloride single drug or combined treatment has been designated as the first-line or second-line treatment option for a variety of hematological malignancies by European and American clinical guidelines.
CAS No.
3543-75-7
Formula
C16H22Cl3N3O2
Molecular Mass
394.72400
Exact Mass
393.07800
PSA
58.36000
Logp
4.06660
IUPAC
4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid;hydrochloride
SMILES
CN1C2=C(C=C(C=C2)N(CCCl)CCCl)N=C1CCCC(=O)O.Cl
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Antineoplastic Agents
Chemical and Physical Properties
Melting Point
149-151°C
Appearance
White to off white powder
Export information
HS Code
29339900
Export Rebate
13%
UN No.
UN 2811
DG-Class
6.1
Risk Code
R60-61-22-40
Safety Label
T,Xn
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