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Titan Pharmaceutical Co., Ltd. (Guangdong)
Titan Pharmaceutical Co., Ltd. (Guangdong)
29 YRS
Guangdong, China
Main Products:
Cefuroxime Sodium Salt / Cefuroxime Axetil
Guangdong, China
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Cefuroxime Axetil / CAS 64544-07-6
OVERVIEW
Packaging
10 KG/Fibre Drum
Lead Time
1-2 weeks
Max Capacity
200 MT/Year
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DESCRIPTION
Typical Properties
Summary
It is an esterified derivative of cefuroxime. It is a precursor drug. After oral administration, it is hydrolyzed by nonspecific esterase to release cefuroxime. Therefore, its antibacterial spectrum and antibacterial activity are similar to cefuroxime, but its absorption in vivo is improved. It has antibacterial effect on a variety of Gram-positive bacteria, Gram-negative bacteria and anaerobic bacteria. Clinically, it is mainly used for respiratory tract infection, urinary tract infection, gonococcal infection, skin and soft tissue infection caused by sensitive bacteria.
CAS No.
64544-07-6
Formula
C20H22N4O10S
Molecular Mass
510.47400
Exact Mass
510.10600
PSA
214.36000
Logp
0.86080
IUPAC
1-acetyloxyethyl (6R,7R)-3-(carbamoyloxymethyl)-7-[[(2E)-2-(furan-2-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
SMILES
CC(OC(=O)C)OC(=O)C1=C(CSC2N1C(=O)C2NC(=O)C(=NOC)C3=CC=CO3)COC(=O)N
Attribute classification
Matter Classification
organic
Category
API & Intermediate > Antibiotics
Chemical and Physical Properties
Melting Point
175-180 °C
Density
1.61 g/cm3
Boiling Point
250°C (rough estimate)
Appearance
White to off white powder
Export information
HS Code
29419059
Export Rebate
13%
Export Formalities
Q
UN No.
0.0
DG-Class
0.0
Risk Code
R36/37/38
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