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Zhejiang Haisen Pharmaceutical Co., Ltd.

26 YRS

Zhejiang, China

CNY 11 Million

149850 m²

500-1000 people

Main Products: Metamizole Sodium / Sucralfate / Antipyrine / Aminopyrine / 2-Hydroxy-4-Amino Butanoic Acid / L-Glutamine / Paroxetine Hydrochloride / Atorvastatin Calcium / Parecoxib Sodium / Propyphenazone / Paroxetine

Zhejiang, China

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Parecoxib Sodium / CAS 198470-85-8

Enterprise standard

OVERVIEW

Packaging

5 KG/Carton

Lead Time

14-30 days

Max Capacity

300 MT/Year

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DESCRIPTION

Typical Properties

Parecoxib Sodium is a water-soluble, injectable sodium salt form of parecoxib, an amide prodrug of the cyclooxygenase II (COX-2) selective, non-steroidal anti-inflammatory drug (NSAID) valdecoxib, with anti-inflammatory, analgesic, and antipyretic activities. Upon intravenous or intramuscular administration, parecoxib is hydrolyzed by hepatic carboxyesterases to its active form, valdecoxib. Valdecoxib selectively binds to and inhibits COX-2. This prevents the conversion of arachidonic acid into prostaglandins, which are involved in the regulation of pain, inflammation, and fever. This NSAID does not inhibit COX-1 at therapeutic concentrations and, therefore, does not interfere with blood coagulation.

CAS No.

198470-85-8

Formula

C19H17N2NaO4S

Molecular Mass

392.40400

Exact Mass

392.08100

PSA

85.62000

Logp

5.39680

IUPAC

sodium;[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)phenyl]sulfonyl-propanoylazanide

SMILES

CCC(=O)[N-]S(=O)(=O)C1=CC=C(C=C1)C2=C(ON=C2C3=CC=CC=C3)C.[Na+]

Matter Classification

organic

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