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Zhejiang Jiangbei Pharmaceutical Co., Ltd.

31 YRS

Zhejiang, China

CNY 36.1 Million

39960 m²

100-500 people

Main Products: Simvastatin / Atorvastatin Calcium Trihydrate / Darunavir / 6,6-Dimethyl-3-Azabicyclo[3.1.0]Hexane

Zhejiang, China

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Darunavir / CAS 206361-99-1

OVERVIEW

Packaging

25 KG/Fibre Drum

Lead Time

14-30 days

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DESCRIPTION

Darunavir

Chinese Name: 达芦那韦

CAS No.: 206361-99-1

Molecular formula: C27H37N3O7S

Molecular weight: 547.66

EINECS No.: 606-590-1

Melting point: 74-76 ℃

Density: 1.34g/cm3

Purpose: a new non peptide antiretroviral protease inhibitor for AIDS treatment.

Typical Properties

Darunavir is an antiretroviral protease inhibitor that is used in the therapy and prevention of human immunodeficiency virus (HIV) infection and the acquired immunodeficiency syndrome (AIDS). Darunavir can cause transient and usually asymptomatic elevations in serum aminotransferase levels and has been linked to rare instances of clinically apparent, acute liver injury. In HBV or HCV coinfected patients, highly active antiretroviral therapy with darunavir may result of an exacerbation of the underlying chronic hepatitis B or C.

CAS No.

206361-99-1

Formula

C27H37N3O7S

Molecular Mass

547.66400

Exact Mass

547.23500

PSA

148.80000

Logp

4.42820

IUPAC

[(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate

SMILES

CC(C)CN(CC(C(CC1=CC=CC=C1)NC(=O)OC2COC3C2CCO3)O)S(=O)(=O)C4=CC=C(C=C4)N

Matter Classification

organic

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