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Dijia Pharmaceutical Group Co., Ltd.

11 YRS

Shandong, China

CNY 585 Million

1065600 m²

500-1000 people

Main Products: 2-N-Propyl-4-Methyl-6-(1’-Methylbenzimidazol-2’-Yl)Benzimidazole / 2-(4-Bromomethyl)Phenylpropionic Acid / 6-Carboxy-4-Methyl-2-Propylbenzimidazole / Methyl 2-Oxocyclopentanecarboxylate

Shandong, China

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2-(4-Bromomethyl)Phenylpropionic Acid / CAS 111128-12-2

OVERVIEW

Packaging

25 KG/Fibre Drum

Lead Time

14-30 days

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DESCRIPTION

2 - (4-Bromomethylphenyl) propionic acid

Chinese Name: 2-（4-溴甲基苯基）丙酸

Common Name: 2 - (4-bromomethyl) phenylpropionic acid

Chemical formula:C₁₀H₁₁BrO₂

Molecular weight: 243.10

CAS No.: 111128-12-2

Purpose: to synthesize the key intermediate of loxoprofen sodium.

Typical Properties

2-[4-(Bromomethyl)phenyl]propanoic acid is a key pharmaceutical intermediate for the synthesis of loxoprofen from toluene by Friedel crafts, willgerodt Kindler hydrolysis "one pot method", monomethylation and bromination. Loxoprofen is a non steroidal anti-inflammatory drug. It is used for analgesia and anti-inflammatory after operation, trauma and tooth extraction.

CAS No.

111128-12-2

Formula

C10H11BrO2

Molecular Mass

243.09700

Exact Mass

241.99400

PSA

37.30000

Logp

2.76960

IUPAC

2-[4-(bromomethyl)phenyl]propanoic acid

SMILES

CC(C1=CC=C(C=C1)CBr)C(=O)O

Matter Classification

organic

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