Erythromycin

Introduction:

Erythromycin, produced by streptomycin, is an alkaline antibiotic. These include erythromycin A (ERA), erythromycin B (ERB), erythromycin C (ERC), erythromycin D (ERD), erythromycin e (ERE) and erythromycin f (ERF). Its free base is for oral use and lactose acid salt can be used for injection. It belongs to macrolide narrow-spectrum antibiotics. It is commonly used for Gram-positive bacteria resistant to penicillin and substitutes allergic to penicillin. The antibacterial spectrum is similar to penicillin.

Physical and chemical properties:

White or off white crystalline powder; Odorless and bitter; Slightly hygroscopic; Weakly alkaline, slightly soluble in water (about 0.2%), easily soluble in organic solvents. Unstable under acidic conditions.

CAS：114-07-8

Molecular formula: C37H67NO13

Molecular weight: 733.93

Structural type:

Purpose:

Erythromycin can treat digestive system diseases, and em can promote the whole gastrointestinal tract to varying degrees. It mainly has the following effects: promoting esophageal contraction and increasing lower esophageal sphincter pressure (LESP); Promote the contraction of gastric antrum and improve the coordination of gastric antrum and duodenum function; Induce gastrointestinal transit complex movement; Promote colon movement and gallbladder contraction. Therefore, it can effectively treat gastrointestinal diseases.