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Hunan Zhongqi Pharmaceutical Co., Ltd.

20 YRS

Hunan, China

CNY 13 Million

39960 m²

Less than 50 people

Main Products: Tolcapone / 3',5'-Cyclic Amp / Nimustine Hydrochloride / Potassium Sodium Dehydroandrographolide Succinate / ((5-Thiazolyl)Methyl)-(4-Nitrophenyl)Carbonate / 4-Cyanotetrahydro-4H-Pyran / 3-(4-Phenoxyphenyl)-1H-Pyrazolo[3,4-d]Pyrimidin-4-Amine / Toluene-4-Sulfonic Acid (R)-(Tetrahydro-Furan-3-Yl) Ester / N-(4-Nitrophenoxycarbonyl)-L-Valine Methyl Ester / 5-Chloromethyl-2-Isopropyl-Thiazole

Hunan, China

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Nimustine Hydrochloride / CAS 55661-38-6

OVERVIEW

Packaging

1 KG/BOTTLE

Lead Time

14-30 days

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DESCRIPTION

Nimustine Hydrochloride

Synonymous：N’-[(4-Amino-2-methyl-5-pyrimidinyl) methyl]-N-(2-chloroethyl)-N-nitrosourea hydrochloride

Structure：

Molecular Formula： C₉H₁₃ClN₆O₂.HCl

Molecular Weight：309.16

CAS Number：55661-38-6

NMPA approval No.：H20059514

National Drug standards：YBH37442005

Test	CP	Results
Color & Appearance	white to light yellow crystalline powder	white crystalline powder
Infrared spectrum	consistent with the structure	Conforms
Assay (HPLC )	NLT 99.0 %	99.5 %
Total impurities (HPLC)	NMT 1.0%	0. 5 %
Unknown impurities ( individual )	NMT 0.1%	0.06 %
pH	3.2～4.2	3.7
Loss on Drying	NMT 0.5 %	0.3 %
Residue on ignition	NMT 0.1%	0.05%
Heavy metals (as Pb)	NMT 10 ppm	Conforms

Package: 1 kg

Storage ：Preserve in tight, light-resistant containers ,and store at temperature below 20℃

Typical Properties

Nimustine hydrochloride is a pyrimidine nitrourea antitumor drug. Together with other nitrourea drugs, ramustine, carmustine, simustine, lomustine, formustine and estrogen sodium phosphate are the main drugs for the treatment of intracranial tumors and meningeal leukemia. This product is a nitrourea alkylating agent, which can alkylate DNA, prevent DNA repair and change RNA structure, Change the protein and enzyme structure and function of target cells, so as to play an anti-tumor role.

CAS No.

55661-38-6

Formula

C9H14Cl2N6O2

Molecular Mass

309.15200

Exact Mass

308.05600

PSA

113.57000

Logp

2.57310

IUPAC

3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-1-(2-chloroethyl)-1-nitrosourea;hydrochloride

SMILES

CC1=NC=C(C(=N1)N)CNC(=O)N(CCCl)N=O.Cl

Matter Classification

organic

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