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Home > API & Intermediate > Synthetic Anti Infective Drugs > Tenofovir Disoproxil Manufacturers > Tenofivir Disoproxil Fumarate(TDF)

Tenofivir Disoproxil Fumarate(TDF)

CAS NO.： 201341-05-1

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Specification： USP

Documentation： Get COA after inquiry

Lead Time： 14-30 days

Max Capacity： -

Packing： 25KG/Fibre Drum

Product Detail

Properties

Tenofivir Disoproxil Fumarate(TDF)

English Name: Tenofivir disoproxil fumarate

CAS No.: 201341-05-1

Molecular formula: C19H30N5O10P

Molecular weight: 519.44

EINECS No.: 606-442-6

Purpose: it is used in combination with other antiretroviral drugs to treat human immunodeficiency virus (HIV) infection.

Properties

Tenofovir dipivoxil fumarate, a water-soluble diester precursor of tenofovir, is developed by Gillette Company. In 2008, the FDA approved tenofovir dipivoxil for the treatment of chronic hepatitis B. In 2014, it was approved by CFDA for the treatment of chronic hepatitis B patients in adults and children ≥ 12 years old (weight ≥ 35kg). Tenofovir dipivoxil is a powerful and highly resistant gene barrier drug. It is recommended by the international authoritative liver disease treatment guidelines for the first-line antiviral treatment of chronic hepatitis B. It has excellent clinical efficacy, good tolerance and sufficient evidence-based basis.

CAS No.

201341-05-1

Formula

C19H30N5O10P

Molecular Mass

519.44300

Exact Mass

519.17300

PSA

195.25000

Logp

3.61680

IUPAC

[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-(propan-2-yloxycarbonyloxymethoxy)phosphoryl]oxymethyl propan-2-yl carbonate

Matter Classification

organic

Category

Density

1.45±0.1 g/cm3(Predicted)

Boiling Point

642.7±65.0 °C(Predicted)

Flash Point

342.5ºC

Appearance

White powder

HS Code

29420000

UN No.

0.0

DG-Class

0.0

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Shijiazhuang Lonzeal Pharmaceuticals Co.,Ltd.

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CRO

Country/Region：

Hebei, China

Contacts：

Manager Wei

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Sales Manager

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