1-Adamantanamine Hydrochloride

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CAS NO.： 665-66-7

FOB Price： NEGOTIABLE Get Latest Price

Specification： 99%

Documentation： Get COA after inquiry

Lead Time： 14-30 days

Max Capacity： -

Packing： 25KG/Fibre Drum

Product Detail

Properties

1-Adamantanamine hydrochloride
Synonymy	AMANTADINE HCL
CAS #	665-66-7
Structural Formula
Appearance	Crystalline Solid
Assay	≥99.0%
Melting Point	300℃
Water	≤0.5%
Package	25Kg/cardboard drum

Properties

Amantadine Hydrochloride is the hydrochloride salt of amantadine, a synthetic tricyclic amine with antiviral, antiparkinsonian, and antihyperalgesic activities. Amantadine appears to exert its antiviral effect against the influenza A virus by interfering with the function of the transmembrane domain of the viral M2 protein, thereby preventing the release of infectious viral nucleic acids into host cells; furthermore, this agent prevents virus assembly during virus replication. Amantadine exerts its antiparkinsonian effects by stimulating the release of dopamine from striatal dopaminergic nerve terminals and inhibiting its pre-synaptic reuptake. This agent may also exert some anticholinergic effect through inhibition of N-methyl-D-aspartic acid (NMDA) receptor-mediated stimulation of acetylcholine, resulting in antihyperalgesia.

CAS No.

665-66-7

Formula

C10H18ClN

Molecular Mass

187.71000

Exact Mass

187.11300

PSA

26.02000

Logp

3.41620