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English Name: 2,4,5-Trifluorophenylacetic acid
CAS No.: 209995-38-0
Molecular formula: C8H5F3O2
Molecular weight: 190.12
EINECS No.: 466-070-3
Melting point: 121-125 ° C
Boiling point: 255.0 ± 35.0 ° C (predicted)
Density: 1.468 ± 0.06 g / cm3 (predicted)
Application: 2, 4, 5- three fluoro acetic acid is a white solid, which is used to synthesize the intermediate of sitagliptin, a new drug for the treatment of type II diabetes. Sitagliptin is the first DPP-IV inhibitor of Merck company. It has good efficacy, side effects, safety and tolerance, and has broad market prospects.
Manufacturing
