(E)-6-Iodo-3-[2-(Pyridin-2-yl)Ethenyl]-1-(Tetrahydro-2H-Pyran-2-yl)-1H-Indazole

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CAS NO.： 886230-77-9

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Product Detail

Properties

Chinese name: (E)-6-Iodo-3-[2-(pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole

English name:(E)-6-Iodo-3-[2-(pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole

CAS number: 886230-77-9

Molecular formula: C19H18IN3O

Molecular weight: 431.27

Density: 1.6 g/cm3

Boiling point: 561.2C at 760 mmHg

Flash point: 293.2 C

Appearance: white powder

Uses: pharmaceutical intermediates

Properties

(E) - 6-iodine-3 - [2 - (pyridin-2-yl) vinyl] - 1 - (tetrahydro-2h-pyran-2-yl) - 1h-indazole is an intermediate for the preparation of acitinib (A794650) as a tyrosine kinase inhibitor. Acitinib is used in cancer treatment.

CAS No.

886230-77-9

Formula

C19H18IN3O

Molecular Mass

431.27000

Exact Mass

431.04900

PSA

39.94000

Logp

4.90540

IUPAC

6-iodo-1-(oxan-2-yl)-3-[(E)-2-pyridin-2-ylethenyl]indazole

Matter Classification

organic

Category

Density

1.6

Boiling Point

561.2ºC at 760 mmHg

Flash Point

293.2ºC

Acidity and Basicity

alkalinity

HS Code

29349990

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