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English Name: (1R, 2S, 5S) - 6,6-dimethyl-3-aza-bicyclo [3.1.0] hexane-2-carboxylic acid methyl ester hydrochloride
CAS No.: 565456-77-1
Molecular formula: C9H15NO2.ClH
Molecular weight: 205.683
EINECS No.: 611-400-5
Introduction: the intermediate of boprivir, namely (1R, 2S, 5S) - 6,6-dimethyl-3-azabicyclo [3.1.0] hexane-2-carboxylic acid methyl ester hydrochloride, is the side chain of boprivir. Boprivir is a pseudo hepatitis C protease inhibitor developed by Schering ploug, which can be used as the main drug of triple therapy (with polyethylene glycol) α- Interferon combined with ribavirin) is used in the treatment of CHC gene type I chronic hepatitis. The combination of the three drugs can cure more than 60% of patients, and polyethylene glycol alone α- The cure rate of interferon or ribavirin is 2 to 3 times that of interferon, and boprivir can improve the cure rate and shorten the treatment time.
CDMO
