Sulbactam acid is β- Lactamase inhibitors have strong and irreversible inhibitory effects on penicillinase and cephalosporinase. Its antibacterial activity is very weak, so it is rarely used alone, and often combined with other antibiotics β- The combination of lactam antibiotics has obvious synergistic effect on most drug-resistant bacteria. For example, sulbactam acid combined with cefoperazone is used to treat drug-resistant bacterial infections, and ampicillin combined with sulbactam acid combined with cefoperazone is used to treat drug-resistant bacterial infections.For synthesis of sulbactam sodium