2-[4-(1,3-Benzodioxol-5-Ylmethyl)Piperazin-1-Yl]Pyrimidine

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CAS NO.： 3605-01-4

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Specification： CP

Documentation： Get COA after inquiry

Lead Time： 14-30 days

Max Capacity： -

Packing： 25KG/Fibre Drum

Product Detail

Properties

Name：Piribedil

Molecular formula:C16H18N4O2

Structural formula：

Molecular weight: 298.34000

Exact mass: 298.14300

PSA：50.72000

LogP：1.53040

Physicochemical properties

Density: 1.304 g / cm3

Boiling point: 469.4 º C at 760 mmHg

Flash point: 237.7 º C

Appearance: crystal powder

Color: white off white

Storage condition: sealed in dry, 2-8 ° C

Properties

Piribedil is a kind of peripheral and cerebral vasodilator commonly used in clinic. It is a dopamine receptor agonist. It can be used alone or in combination with levodopa in the treatment of Parkinson's disease. It can improve some symptoms caused by intelligence deficiency in the elderly, such as decreased attention and memory, vertigo, intermittent claudication (stage 2) caused by arterial embolism of lower limbs. Retinal defect attack, improve visual acuity, similar to dopamine, side effects similar to levodopa. In addition, this product can also improve the peripheral blood circulation, and has certain curative effect on obstructive or embolic fundus diseases. Piribedil can stimulate the postsynaptic D2 receptors in substantia nigra and striatum, and D2 and D3 receptors in midbrain cortex and midbrain limbic lobe pathway to provide effective dopamine effect. During the treatment, piribedil stimulates cortical electrogenesis in the form of "dopaminergic", which has clinical effect on various functions induced by dopamine. For the peripheral circulation, the drug can increase the blood flow of femoral vessels, which may be due to the inhibition of sympathetic tension.

CAS No.

3605-01-4

Formula

C16H18N4O2

Molecular Mass

298.34

Exact Mass

298.14300

PSA

50.72000

Logp

1.53040

IUPAC

2-[4-(1,3-benzodioxol-5-ylmethyl)piperazin-1-yl]pyrimidine

Matter Classification

organic

Category

Melting Point

98 °C

Density

1.3 g/cm3

Boiling Point

469.4 ºC

Flash Point

237.7 ºC

Appearance

white solid

Acidity and Basicity

alkalinity

HS Code

29349990

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