Guanfacine Hydrochloride

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CAS NO.： 29110-48-3

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Specification： CP

Documentation： Get COA after inquiry

Lead Time： 14-30 days

Max Capacity： -

Packing： 25KG/Fibre Drum

Product Detail

Properties

English Name: Guanfacine Hydrochloride

Chemical formula: C9H10Cl3N3O

Structural formula：

CAS accession No.: 29110-48-3

Melting point: 215-217 ℃

RTECS No.: cy1481000

Storage conditions: inertia, roomtemperature

Solubility: H2O: 12mg chemicalbook / mlat60 ° C, soluble

Color: white

Merck：14,4561

InChIKey：DGFYECXYGUIODH-UHFFFAOYSA-N

Dangerous goods transport No.: 3249

WGKGermany：3

HazardClass:6.1(b)

PackingGroupChemicalbook:III

Customs Code: 2925294500

Toxicity ld50inch: 165mg / kgorally (reward)

Properties

Guanfacine hydrochloride is a central antihypertensive drug, and its pharmacological effect is similar to clonidine. It is a kind of center α 2 receptor activator, activation center α 2 receptors, reduce peripheral sympathetic activity, resulting in decreased blood pressure. The antihypertensive effect of this drug is weaker than that of clonidine. Therefore, the dose is 7 ~ 10 times higher than that of clonidine, and the sedative effect of pivot nervous system is also weak, and the action site may be different from that of clonidine.

CAS No.

29110-48-3

Formula

C9H10Cl3N3O

Molecular Mass

282.55400

Exact Mass

280.98900

PSA

78.97000

Logp

3.53850

IUPAC

N-(diaminomethylidene)-2-(2,6-dichlorophenyl)acetamide;hydrochloride

Matter Classification

organic

Category

Melting Point

215-217℃

Appearance

white powder

HS Code

29252900

UN No.

3249

DG-Class

6.1(b)

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