Synopsis：Isosorbide Mononitrate is the common name of 1,4:3,6-didehydrated-d-sorbitol-5 mononitrate, also known as isosorbide 5-nitrate. It is the main bioactive metabolite of isosorbide dinitrate. The main pharmacological action is to relax vascular smooth muscle. The clinical dosage forms of include: ordinary tablets, sustained-release preparations and injections, which are mainly used for the long-term treatment of guanye disease; Prevention of angina pectoris; Treatment of persistent angina pectoris after myocardial infarction; Combined with digitalis or diuretics to treat chronic congestive heart failure; To treat simple systolic hypertension, hypertensive crisis and perioperative acute hypertension in the elderly.
Structural formula:
Properties
Summary
Isosorbide mononitrate is the common name of 1,4:3,6-didehydrated-d-sorbitol-5 mononitrate, also known as isosorbide 5-nitrate. It is the main bioactive metabolite of isosorbide dinitrate. The main pharmacological action is to relax vascular smooth muscle. The clinical dosage forms of include: ordinary tablets, sustained-release preparations and injections, which are mainly used for the long-term treatment of guanye disease; Prevention of angina pectoris; Treatment of persistent angina pectoris after myocardial infarction; Combined with digitalis or diuretics to treat chronic congestive heart failure; To treat simple systolic hypertension, hypertensive crisis and perioperative acute hypertension in the elderly.
CRO
