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Home > API & Intermediate > Pharmaceutical Intermediates > ((5-Thiazolyl)Methyl)-(4-Nitrophenyl)Carbonate Manufacturers > Carbonic acid 4-nitrophenyl 5-thiazolylmethyl ester

Carbonic acid 4-nitrophenyl 5-thiazolylmethyl ester

CAS NO.： 144163-97-3

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Specification： ≥98.0%

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Lead Time： 14-30 days

Max Capacity： -

Packing： 25KG/Fibre Drum

Product Detail

Properties

Carbonic acid 4-nitrophenyl 5-thiazolylmethyl ester

CAS：144163-97-3

Molecular Formula：C₁₁H₈N₂O₅S

Molecular Weight：280.26

Structure：

Properties

(4-Nitrophenyl) 1,3-thiazol-5-ylmethyl carbonate is used as an intermediate of ritonavir. Ritonavir is an effective oral inhibitor of human immunodeficiency virus-1 (HIV-1) and human immunodeficiency virus-2 (HIV-2) aspartate protease. Blocking the enzyme can promote the production of polyproteins required for morphologically mature HIV particles, so that HIV particles remain immature, thus slowing down the spread of HIV in cells, In order to prevent a new round of infection and delay the development of the disease.

CAS No.

144163-97-3

Formula

C11H8N2O5S

Molecular Mass

280.25700

Exact Mass

280.01500

PSA

122.48000

Logp

3.29010

IUPAC

(4-nitrophenyl) 1,3-thiazol-5-ylmethyl carbonate

Matter Classification

organic

Category

Melting Point

126-127 ºC

Density

1.485 g/cm3

Boiling Point

475.3 ºC

Flash Point

241.3 ºC

Appearance

Gray to yellow solid

Acidity and Basicity

neutral

HS Code

29341090

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Hunan Zhongqi Pharmaceutical Co., Ltd.

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Manufacturing

Country/Region：

Hunan, China

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Manager Zhu

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Sales Manager

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0086-730-8722288

Email：

zhongqi@chemmail.net

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