Bendamustine Hydrochloride

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CAS NO.： 3543-75-7

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Specification： 99%

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Lead Time： In Stock

Max Capacity： 10MT/Year

Packing： 25KG/Fibre Drum

Product Detail

Properties

CBNumber：	CB0777896
Name：	Bendamustine hydrochloride
Chinese Name：	盐酸苯达莫司汀
MF：	C16H22Cl3N3O2
MW：	394.72
CAS：	3543-75-7

Properties

Bendamostine hydrochloride was first developed by ozegowski and his colleagues in the microbial experimental Association in Jena, Germany in the early 1860s. The initial purpose was to connect an alkylated nitrogen mustard (a non effective alkylating agent) with a purine and an amino acid. Compared with nitrogen mustard phenylbutyrate, the main advantage of the newly synthesized compound is its water solubility. It was widely used, but until the end of the cold war, the drug has been carried out in Europe for many single drugs or other drugs for the treatment of various hematological malignancies or non Hodgkin's lymphoma, multiple myeloma, CLL and breast cancer. The clinical effect is very significant, significantly reducing the rate of recurrence and mortality, and has little side effects. Good security. So far, bendamostine hydrochloride single drug or combined treatment has been designated as the first-line or second-line treatment option for a variety of hematological malignancies by European and American clinical guidelines.

CAS No.

3543-75-7

Formula

C16H22Cl3N3O2

Molecular Mass

394.72400

Exact Mass

393.07800

PSA

58.36000

Logp

4.06660

IUPAC

4-[5-[bis(2-chloroethyl)amino]-1-methylbenzimidazol-2-yl]butanoic acid;hydrochloride

Matter Classification

organic

Category

Melting Point

149-151°C

Appearance

White to off white powder

Acidity and Basicity

acidness

HS Code

29339900

UN No.

UN 2811

DG-Class

6.1

Risk Code

R60-61-22-40

Safety Label

T,Xn

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