Introduction: It is a potent and selective inhibitor of glucosylceramide synthase (GCS) and ceramide glucosyltransferase (CGT).
Structural formula:
Properties
Summary
A selective allosteric inhibitor of glucoceramide synthase (GCS) that can pass through the blood-brain barrier. It can be used to study Parkinson's disease, Fabry's disease and Gaucher's disease.