Synopsis:Candesartan axetil was rapidly decomposed into the active metabolite candesartan in vivo. Candesartan is an angiotensin Ⅱ at receptor antagonist. It antagonizes the contraction of angiotensin Ⅱ by binding to at receptor of vascular smooth muscle, so as to reduce peripheral vascular resistance. It is suitable for essential hypertension.
Structural formula:
Properties
Summary
Candesartan axetil was rapidly decomposed into the active metabolite candesartan in vivo. Candesartan is an angiotensin Ⅱ at receptor antagonist. It antagonizes the contraction of angiotensin Ⅱ by binding to at receptor of vascular smooth muscle, so as to reduce peripheral vascular resistance. It is suitable for essential hypertension.
Manufacturing
