6-Acetoxy-7-Methoxy-3,4-Dihydroquinazolin-4(3H)-one

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Home > API & Intermediate > Pharmaceutical Intermediates > 3,4-Dihydro-7-Methoxy-4-Oxoquinazolin-6-yl Acetate Manufacturers > 6-Acetoxy-7-Methoxy-3,4-Dihydroquinazolin-4(3H)-one

6-Acetoxy-7-Methoxy-3,4-Dihydroquinazolin-4(3H)-one

CAS NO.： 179688-53-0

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Product Detail

Properties

6-Acetoxy-7-Methoxy-3,4-Dihydroquinazolin-4(3H)-one

Product Name: 6-Acetoxy-7-Methoxy-3,4-Dihydroquinazolin-4(3H)-one

CAS NO：179688-53-0

Molecular formula: C11H10N2O4

Molecular weight: 234.20

Appearance: white to light brown solid

Application: used as intermediate of Gefitinib.

Properties

3,4-dihydro-7-methoxy-4-oxoquinazoline-6-ol acetate can be used as an intermediate in pharmaceutical synthesis. It can be prepared from 6-hydroxy-7-methoxy-4-ketoquinazoline as reaction raw material and can be used to prepare intermediate 7-methoxy-6-acetoxy-4-chloroquinazoline.

CAS No.

179688-53-0

Formula

C11H10N2O4

Molecular Mass

234.20800

Exact Mass

234.06400

PSA

81.28000

Logp

0.85700

IUPAC

(7-methoxy-4-oxo-3H-quinazolin-6-yl) acetate

Matter Classification

organic

Category

Melting Point

293 °C

Density

1.39

Boiling Point

452.391ºC at 760 mmHg

Flash Point

227.398ºC

Appearance

White to light brown solid

Acidity and Basicity

alkalinity

HS Code

29339900

UN No.

0.0

DG-Class

0.0

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