4-Hydroxy-7-Phenoxy-3-Isoquinolinecarboxylic Acid Methyl Ester

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4-Hydroxy-7-Phenoxy-3-Isoquinolinecarboxylic Acid Methyl Ester

CAS NO.： 1455091-10-7

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Specification： 98.0%

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Lead Time： 14-30 days

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Packing： 25KG/Fibre Drum

Product Detail

Properties

Chinese name: Methyl 4-Hydroxy-7-Phenoxy-3-Isoquinolinecarboxylate

English name:4-Hydroxy-7-Phenoxy-3-Isoquinolinecarboxylic Acid Methyl Ester

CAS number: 1455091-10-7

Molecular formula: C18H15NO4

Molecular weight: 298.77

Appearance: light yellow or off-white solid

Usage:Intermediate of Roxadustat

Properties

Methyl 4-hydroxy-7-phenoxyisoquinoline-3-carboxylate can be used as an intermediate in pharmaceutical synthesis. The intermediate 5-phenoxyisobenzofuran-1 (3H) - one can be prepared from phenol, and further reacted to prepare methyl 2 - (chloromethyl) - 4-phenoxybenzoate. Methyl 4-hydroxy-7-phenoxyisoquinoline-3-carboxylate can be prepared by reacting with n-p-toluenesulfonylglycine methyl ester.

CAS No.

1455091-10-7

Formula

C17H13NO4

Molecular Mass

295.28900

Exact Mass

295.08400

PSA

68.65000

Logp

3.51930

IUPAC

methyl 4-hydroxy-7-phenoxyisoquinoline-3-carboxylate

Matter Classification

organic

Category

Density

1.320±0.06 g/cm3(Predicted)

Boiling Point

534.7±45.0 °C(Predicted)

Appearance

Light yellow or off white solid

Acidity and Basicity

acidness

HS Code

29334900

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25KG/Fibre Drum

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Jinan Xinke Pharmaceutical Science and Technology Co., Ltd.

9YRS

Business Type：

CRO

Country/Region：

Shandong, China

Contacts：

Manager Ma

Position Title：

Sales manager

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xinke@chemmail.net

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