Sugammadex sodium

Product introduction:

Sugammadex sodium, with the trade name of bridion, is the world's first and only specific binding neuromuscular block antagonist developed by MSD. It is a modified γ- Cyclodextrin forms a complex with neuromuscular blocking drugs rocuronium or vecuronium in plasma, so as to reduce the number of neuromuscular blocking drugs combined with nicotine receptor at neuromuscular junction, so as to antagonize neuromuscular block induced by rocuronium or vecuronium.

CAS：343306-79-6

Molecular formula: C72H104Na8O48S8

Molecular weight: 2177.97

Structural type:

Product purpose: Sugammadex sodium is a selective muscle relaxant, which is mainly used in muscle spastic diseases and high muscle tension diseases. The drug has remarkable effect and quick effect.

Properties

Sugammadex is a kind of γ- Cyclodextrin derivative, whose molecule is composed of lipophilic core and hydrophilic outer end, is a selective muscle relaxant antagonist.

CAS No.

343306-79-6

Formula

C72H104Na8O48S8

Molecular Mass

2178.01000

Exact Mass

2176.26000

PSA

994.80000

Logp

-18.35920

IUPAC

octasodium;3-[[(1S,3S,5S,6S,8S,10S,11S,13S,15S,16S,18S,20S,21S,23S,25S,26S,28S,30S,31S,33S,35S,36S,38S,40S,41R,42R,43R,44R,45R,46R,47R,48R,49R,50R,51R,52R,53R,54R,55R,56R)-10,15,20,25,30,35,40-heptakis(2-carboxylatoethylsulfanylmethyl)-41,42,43,44,45,46,47,48,49,50,51,52,53,54,55,56-hexadecahydroxy-2,4,7,9,12,14,17,19,22,24,27,29,32,34,37,39-hexadecaoxanonacyclo[36.2.2.23,6.28,11.213,16.218,21.223,26.228,31.233,36]hexapentacontan-5-yl]methylsulfanyl]propanoate

Matter Classification

organic

Category

Density

1.275g/cm3 （计算值）

Appearance

White powder

Acidity and Basicity

neutral

HS Code

29329990

UN No.