Z-8: Diphenyl[4-(4-Fluorophenyl)-6-isopropyl-2-(N-MethylMethylsulfonyl)aMino-pyriMidin-5-yl-Methyl]phosphine Oxide

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Home > API & Intermediate > Pharmaceutical Intermediates > N-[5-(Diphenylphosphorylmethyl)-4-(4-Fluorophenyl)-6-Propan-2-Ylpyrimidin-2-Yl]-N-Methylmethanesulfonamide Manufacturers > Z-8: Diphenyl[4-(4-Fluorophenyl)-6-isopropyl-2-(N-MethylMethylsulfonyl)aMino-pyriMidin-5-yl-Methyl]phosphine Oxide

Z-8: Diphenyl[4-(4-Fluorophenyl)-6-isopropyl-2-(N-MethylMethylsulfonyl)aMino-pyriMidin-5-yl-Methyl]phosphine Oxide

CAS NO.： 289042-10-0

FOB Price： NEGOTIABLE Get Latest Price

Specification： 99.5%

Documentation： Get COA after inquiry

Lead Time： 14-30 days

Max Capacity： -

Packing： 25KG/Fibre Drum

Product Detail

Properties

Z-8: Diphenyl[4-(4-Fluorophenyl)-6-isopropyl-2-(N-MethylMethylsulfonyl)aMino-pyriMidin-5-yl-Methyl]phosphine Oxide

Chinese name：N-[5-(联苯-膦酰基甲基)-4-(4-氟-苯基)-6-异丙基-嘧啶-2-基]-N-甲基-甲烷磺胺；瑞舒伐他汀中间体Z-8

CAS NO：289042-10-0

Molecular formula：C₂₈H₂₉FN₃O₃PS

Molecular weight：537.58

Boiling point：679.125 ºC

Density：1.322 g/cm3

Application：Rosuvastatin intermediates

Properties

This product is the intermediate of rosuvastatin calcium. Rosuvastatin calcium is a selective 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor. By inhibiting HMG CoA reductase, rosuvastatin calcium can reduce the synthesis and storage of cholesterol in hepatocytes, thereby reducing the levels of total cholesterol and low density lipoprotein cholesterol in blood.

CAS No.

289042-10-0

Formula

C28H29FN3O3PS

Molecular Mass

537.58500

Exact Mass

537.16500

PSA

98.42000

Logp

6.39680

IUPAC

N-[5-(diphenylphosphorylmethyl)-4-(4-fluorophenyl)-6-propan-2-ylpyrimidin-2-yl]-N-methylmethanesulfonamide

Matter Classification

organic

Category

Density

1.322 g/cm3

Boiling Point

679.125 ºC

Flash Point

364.522 ºC

Appearance

white solid

Acidity and Basicity

alkalinity

HS Code

29359000

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Zhejiang Hongyuan Pharmaceutical Co., Ltd.

19YRS

Business Type：

Manufacturing

Country/Region：

Zhejiang, China

Contacts：

Manager Liu

Position Title：

Manager of foreign trade department

Tel：

0086-571-88278599

Email：

Hongyuan.Liu@chemmail.net

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